Porous HA scaffolds for drug releasing

• Tipo: Artigo em Revista Científica Internacional
• Data: 2005

Autores

Queiroz, AC (Autor) Outra; Santos, JD (Autor) FEUP; Monteiro, FJ (Autor) FEUP

Revista

A Revista está pendente de validação pelos Serviços Administrativos.

Título: BIOCERAMICS, VOL 17

Vol. 28

Páginas: 407-410

Indexação

ISI Web of Knowledge - 8 Citações

ISI Web of Science

Scopus - 7 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia dos materiais

Outras Informações

ID Authenticus: P-000-58A

Abstract (EN): Dense and porous hydroxyapatite materials aimed at being used in controlled drug delivery, were characterised and studied in order to evaluate their ability to adsorb and release sodium ampicillin in a controlled manner, as a model for a drug delivery system, potentially applicable associated to surgery for the treatment of bone defects. These porous materials should also have adequate mechanical strength to withstand manipulation and sculpturing in surgery room. Adsorption and release profiles were obtained for a range of porous materials, leading to higher adsorption rates and more adequate release profiles than for dense materials.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4