Deficiency of vitamins C and E in women of childbearing age in Brazil: a systematic review and meta-analysis

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2021

Autores

Lucchetta, RC (Autor) Outra; Cavicchioli, SdA (Autor) Outra; Gini, ALR (Autor) Outra; Forgerini, M (Autor) Outra; Varallo, FR (Autor) Outra; Nadai, MNd (Autor) Outra; Fernandez-Llimos, F (Autor) FFUP; Mastroianni, PdC (Autor) Outra

Revista

Título: Sao Paulo Medical Journal

Vol. 139

Páginas: 545-555

ISSN: 1516-3180

Editora: Associação Paulista de Medicina

Indexação

ISI Web of Knowledge - 2 Citações

Scopus - 2 Citações

Outras Informações

ID Authenticus: P-00V-NPV

DOI: 10.1590/1516-3180.2020.0799.r1.0904221

Abstract (EN): BACKGROUND: Despite the several options available for supplements containing vitamins C and E, evidence regarding the prevalence of deficiency or insufficiency of these vitamins is weak. OBJECTIVES: To estimate the prevalence of deficiency or insufficiency of vitamins C and E and associated factors among women of childbearing age, in Brazil. DESIGN AND SETTING: Systematic review and meta-analysis conducted at a Brazilian public university. METHODS: A search from index inception until May 2020 was conducted. Meta-analyses were performed using inverse variance for fixed models, with summary proportions calculation using Freeman-Tukey double arcsine (base case). Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. RESULTS: Our review identified 12 studies, comprising 1,316 participants, especially breastfeeding women. There was at least one quality weakness in all studies, mainly regarding sampling method (i.e. convenience sampling) and small sample size. The prevalence of vitamin C deficiency ranged from 0% to 40%. Only vitamin E deficiency was synthetized in meta-analyses, with mean prevalences of 6% regardless of the alpha-tocopherol cutoff in plasma, and 5% and 16% for cutoffs of < 1.6-12.0 mmol/l and < 16.2 mmol/l, respectively. The cumulative meta-analysis suggested that a trend to lower prevalence of vitamin E deficiency occurred in recent studies. CONCLUSIONS: Although the studies identified in this systematic review had poor methodological and reporting quality, mild-moderate vitamin C and E deficiencies were identified, especially in breastfeeding women. Thus, designing and implementing policies does not seem to be a priority, because the need has not been properly dimensioned among women of childbearing age in Brazil.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11