Listeria infection in patients on anti-TNF treatment: Report of two cases and review of the literature

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2013

Autores

Abreu, C (Autor) FMUP; Magro F (Autor) FMUP; Vitas Boas, F (Autor) Outra; Lopes, S (Autor) Outra; Macedo G (Autor) FMUP; Sarmento A (Autor) FMUP

Revista

Título: Journal of Crohn's and Colitis

Vol. 7

Páginas: 175-182

ISSN: 1873-9946

Editora: Oxford University Press

Indexação

ISI Web of Knowledge - 86 Citações

Scopus - 50 Citações

Outras Informações

ID Authenticus: P-002-09S

DOI: 10.1016/j.crohns.2012.04.018

Abstract (EN): Listeria monocytogenes is an aerobic gram positive intracellular bacillus, predominantly affecting pregnant women, immunocompromised patients and old individuals. Invasive listeriosis, meningitis and meningoencephalitis, bacteraemia with or without joint, eye or heart focalization are clinical manifestations of the disease. Anti-TNF-alpha drugs blocking the hosts response against various microorganisms, particularly intracellular agents like Listeria monocytogenes, increase the risk of disease. We report two cases of L. monocytogenes meningitis in ulcerative colitis patients under infliximab plus steroids. One patient is HIV-1 infected. A review of reported invasive listeriosis cases under anti-TNF drugs is also showed.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8