Non alcoholic fatty liver disease [Doença hepática esteatósica não alcoólica]

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2004

Autores

Lopes, S (Autor) Outra; Macedo G (Autor) Outra

Revista

Título: Arquivos de Medicina

Vol. 18

Página Inicial: 297

ISSN: 0871-3413

Editora: A E F M U P, Alameda prof. H. Montiero

Indexação

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-007-E1H

Abstract (EN): Non alcoholic fatty liver disease (NAFLD) is a clinicopathologic syndrome with increasing significance. It refers to a wide spectrum of hepatic lesions, ranging from steatosis, to steatohepatitis, fibrosis and cirrhosis. It was originally described in obese, diabetic, middle-aged women, who did not drink alcohol, but whose hepatic histology was similar to alcoholic liver disease. This typical patient profile has been expanded and is now recognized to occur in normal weight men without overt abnormalities in carbohydrate metabolism. It is considered one of the most common causes of liver enzymes elevations and it may potentiate liver damage induced by other hepatotoxic agents. There are no specific diagnostic tools, and sometimes the diagnosis is made presumptively, in an obese patient, with elevated transaminases, without any other recognized cause of liver disease. A definitive diagnosis is achieved with liver biopsy. Although initially considered a benign disease it is now known that it can progress to fibrosis, cirrhosis and end-stage liver disease. ©ArquiMed, 2004.

Idioma: Português

Tipo (Avaliação Docente): Científica