Acute generalized exanthematous pustulosis to amoxicillin associated with parvovirus B19 reactivation

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

Calistru, AM (Autor) Outra; Carmen Silva (Autor) FMUP; Ana Cunha (Autor) FMUP; Bettencourt, H (Autor) Outra; Azevedo, F (Autor) Outra

Revista

Título: Cutaneous and Ocular Toxicology

Vol. 31

Páginas: 258-261

ISSN: 1556-9527

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 10 Citações

Scopus - 15 Citações

Outras Informações

ID Authenticus: P-002-6K4

DOI: 10.3109/15569527.2011.645978

Abstract (EN): We report the case of a 22-year-old male patient with 2 episodes, 4 months apart, of acute generalized exanthematous pustulosis (AGEP) associated with oral intake of amoxicillin and simultaneous reactivation of parvovirus B19 infection proven by positive polymerase chain reaction test in the skin fragment and blood sample and elevation of the IgG antibodies titer. To our knowledge, this is the first report of AGEP resulting from the interaction between drug hypersensitivity and the reactivation of parvovirus B19. A combination of an immunological reaction to the drug and virus infection could be responsible for the clinical picture.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4