Effect of Cu-nanoparticles versus one Cu-salt: Analysis of stress biomarkers response in Enchytraeus albidus (Oligochaeta)

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

Gomes, SIL (Autor) Outra; Novais, SC (Autor) Outra; Gravato, C (Autor) Outra; Guilhermino, L. (Autor) ICBAS; Scott Fordsmand, JJ (Autor) Outra; Soares, AMVM (Autor) Outra; Amorim, MJB (Autor) Outra

Revista

Título: Nanotoxicology

Vol. 6

Páginas: 134-143

ISSN: 1743-5390

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 18 Citações

Scopus - 25 Citações

Outras Informações

ID Authenticus: P-002-CWR

DOI: 10.3109/17435390.2011.562327

Abstract (EN): In the present study, the main goal was to compare the effects of ionic copper versus copper nanoparticles in Enchytraeus albidus assessing the effect at the biomarker level, testing different concentrations and exposure times. Measured parameters were lipid peroxidation (LPO), total, reduced and oxidized glutathione content (TG, GSH and GSSG), the enzymatic activity of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx), glutathione S-transferases (GSTs) and cholinesterases (ChEs). Results showed that both salt-and nano-copper caused oxidative stress and damage to E. albidus, as confirmed by LPO levels, and effects could be discriminated between the copper forms. Nevertheless and despite the visible discrimination between nano and the salt form (time and exposure dependent), there was no single or a set of biomarkers that provided the best discrimination.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10