Oxidative stress response in gill and liver of Liza saliens, from the Esmoriz-Paramos coastal lagoon, Portugal

• Tipo: Artigo em Revista Científica Internacional
• Data: 2008

Autores

Fernandes, C (Autor) Outra; Fontainhas Fernandes, A (Autor) Outra; Ferreira, M (Autor) Outra; Maria Antónia Salgado (Autor) ICBAS

Revista

Título: Archives of Environmental Contamination and Toxicology

Vol. 55

Páginas: 262-269

ISSN: 0090-4341

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 28 Citações

Scopus - 41 Citações

Outras Informações

ID Authenticus: P-003-X4J

DOI: 10.1007/s00244-007-9108-z

Abstract (EN): Tissue-specific responses against oxidative stress and lipid peroxidation were analyzed in wild adult mullet (Liza saliens) caught in the Portuguese coastal lagoon Esmoriz-Paramos. Parameters measured were catalase (CAT), superoxide dismutase (SOD), and glutathione-S-transferase (GST) activities in liver and gill tissues and lipid peroxidation. The enzyme activities were related to gill histopathological alterations, as well as to heavy metals (Cu and Zn) concentrations in these tissues. Gill epithelium of L. saliens showed histological alterations, such as epithelial hyperplasia resulting in lamellar fusion, epithelial lifting, vasodilatation, and lamellar aneurisms, with a prevalence ranging from 62% to 92%. The highest Cu content was found in liver (379 mg center dot kg(-1)), while the highest Zn content was observed in gill (119 mg center dot kg(-1)). SOD and CAT activities showed differences between gill and liver. The highest activities found were SOD in gill (10.1 U/mg protein) and CAT in liver (39.2 mmol/min/mg protein). In gill, CAT activity was negatively related to both Cu levels and gill lifting, while a positive relationship was found between SOD activity and fish age. The positive relationship between Cu and CAT activity in liver suggests that an increase in metabolic level is related to Cu-induced oxidative stress. The decrease in gill CAT activity can be due to osmotic stress caused by damaged gill epithelium. CAT activity in liver is an appropriate biomarker of oxidative stress in the Esmoriz-Paramos lagoon.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8