Chitosan: An option for development of essential oil delivery systems for oral cavity care?

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2009

Autores

Andre Sao Pedro (Autor) Outra; Elaine Cabral Albuquerque (Autor) Outra; Domingos Ferreira (Autor) FFUP; Bruno Sarmento (Autor) Outra

Revista

Título: Carbohydrate Polymers

Vol. 76

Páginas: 501-508

ISSN: 0144-8617

Editora: Elsevier

Indexação

ISI Web of Knowledge - 91 Citações

Scopus - 112 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-003-K31

DOI: 10.1016/j.carbpol.2008.12.016

Abstract (EN): Microencapsulation of bioactive compounds has received increased attention in the last decade. Among the polymers used for developing microparticulated systems, chitosan has been widely cited. Obtained by deacetylation of chitin, chitosan is a natural, biodegradable, biocompatible and mucoadhesive polymer with permeability enhancement properties. These data justify its use for overcoming the reduced efficacy of conventional treatments of oral diseases. Various tests simulating the buccal environment have described controlled drug release profile and significant activity against buccal pathogens by chitosan microparticles entrapping antimicrobial agents. Considering the increasing microbial resistance to conventional antibiotics, essential oils have shown to be an important option against these pathogens. For sustained stability and prolonged release of essential oils from pharmaceutical formulations, some authors have studied the association of chitosan to them. This review disserts about the application of chitosan and essential oils on oral cavity care pointing out their association may be an interesting option.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8