Biochemical and metabolic effects of a short-term exposure to nanoparticles of titanium silicate in tadpoles of Pelophylax perezi (Seoane)

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Salvaterra, T (Autor) Outra; Alves, MG (Autor) Outra; Domingues, I (Autor) Outra; Pereira, R (Autor) FCUP; Rasteiro, MG (Autor) Outra; Carvalho, RA (Autor) Outra; Soares, AMVM (Autor) Outra; Lopes, I (Autor) Outra

Revista

Título: Aquatic Toxicology

Vol. 128

Páginas: 190-192

ISSN: 0166-445X

Editora: Elsevier

Indexação

ISI Web of Knowledge - 18 Citações

Scopus - 19 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina básica

Outras Informações

ID Authenticus: P-005-2GM

DOI: 10.1016/j.aquatox.2012.12.014

Abstract (EN): This study aimed to evaluate sublethal effects of a short-term exposure (96 h) to titanium silicate nanoparticles (TiSiO4-NP) on Pelophylax perezi tadpoles. Tadpoles were exposed to five concentrations of TiSiO4-NP (8.2, 10.2, 12.8, 16 and 20 mg/L) plus a control. Effect criteria were: mortality, cholinesterases, glutathione S-transferases, lactate dehydrogenase, and catalase activities, and alanine and lactate contents. Light scattering was used for physical characterization of TiSiO4-NP suspensions, revealing a high aggregation state of the NP, consistent with low z-potential values (<30 mV). Mortality among TiSiO4-NP treatments was <11%. Significant differences relatively to the control were observed at the biochemical level (for CAT and LDH) and in lactate and alanine contents, which may end-up in increased oxidative stress. Overall, some of the monitored endpoints suggest metabolic alterations in TiSiO4-NP exposed tadpoles, highlighting the potential of TiSiO4-NP long-term effects on these organisms.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3