Alterações da Rigidez Arterial em Pacientes com Estenose Aórtica Grave Submetidos à Cirurgia de Troca Valvar

• Tipo: Artigo em Revista Científica Internacional
• Data: 2021

Autores

Raimundo, R (Autor) Outra; Saraiva, F (Autor) Outra; Moreira, R (Autor) Outra; Moreira, S (Autor) Outra; Ferreira, AF (Autor) Outra; Cerqueira, RJ (Autor) Outra; Amorim, MJ (Autor) Outra; Pinho, P (Autor) Outra; Barros, AS (Autor) FMUP; Lourenço, AP (Autor) Outra; Leite-Moreira AF (Autor) FMUP

Revista

Título: Arquivos Brasileiros de Cardiologia

Vol. 116

Páginas: 475-482

ISSN: 0066-782X

Editora: Sociedad Brasileira De Cardiologia

Indexação

ISI Web of Knowledge - 8 Citações

Scopus - 7 Citações

Outras Informações

ID Authenticus: P-00T-KD2

DOI: 10.36660/abc.20190577

Abstract (EN): Background: Little is known about the impact of severe aortic stenosis (AS) in aortic stiffness and if there is any change after removing AS barrier with aortic valve replacement (AVR) surgery. Objective: To estimate carotid-femoral pulse wave velocity (PWV) changes after AVR surgery and to define PWV predictors in severe AS patients. Methods: Single-center retrospective cohort, including patients with severe AS who underwent AVR surgery with bioprostheses, between February 2017 and January 2019 and performed PWV measurements (Complior (R)) before and after the procedure (2 +/- 1 months). Before and after AVR, PWV values were compared through paired tests. The associations of PWV with clinical data were studied and linear regression models were applied to estimate pre and postoperative PWV independent predictors. The significance level was set at 5%. Results: We included 150 patients in the sample, with mean age of 72 +/- 8 years, and 51% being males. We found a statistically significant increase in PWV values after surgery (9.0 +/- 2.1 m/s vs. 9.9 +/- 2.2, p<0.001, before and after AVR, respectively) and an inverse association with AS severity variables. In the linear regression model, age and systolic blood pressure (SBP) were established as independent predictors of higher pre- and postoperative PWV, while higher mean valvular gradient emerged as a determinant of lower pre-AVR PWV. Conclusion: We documented an inverse correlation of arterial stiffness with the severity of AS in patients with AS, and a significant increase in PWV values after AVR surgery. Advanced age and higher SBP were associated with higher PWV values, although arterial function measurements were within the normal range.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8