Multidrug-resistant high-risk Enterococcus faecium clones: can we really define them?

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2021

Autores

Freitas, AR (Autor) Outra; Pereira, AP (Autor) Outra; Novais, Carla (Autor) FFUP; Luisa Peixe (Autor) FFUP

Revista

Título: International Journal of Antimicrobial Agents

Vol. 57

ISSN: 0924-8579

Editora: Elsevier

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 1 Citação

Outras Informações

ID Authenticus: P-00T-6R4

DOI: 10.1016/j.ijantimicag.2020.106227

Abstract (EN): Enterococcus faecium is a significant opportunistic human pathogen with a broad host range, including humans, farm animals, pets and wildlife. Specialised subpopulations have globally evolved towards a powerful and convergent adaption to the healthcare environment by acquiring a cocktail of key antimicrobial resistance and virulence genes, enabling them to thrive in the disturbed microbiota of hospitalised patients. These populations can also be found in different community reservoirs, but the relevance of their dispersal in non-human hosts is greatly unknown and is here discussed. This review provides a brief historical overview of what we have been considering E. faecium high-risk clones worldwide alongside the advances in strain typing technologies that have revolutionised our understanding of the genetic evolution of this species over the last three decades.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8