The usual suspect-malaria? Diagnostic challenges in post-artesunate delayed haemolysis: a clinical laboratory perspective through a case report

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2025

Autores

Molnar, E (Autor) Outra; Cabral, PM (Autor) Outra; Portal, F (Autor) Outra; Guimarães, A (Autor) FMUP; Santos, L (Autor) FMUP; Guimarães, JT (Autor) FMUP

Revista

Título: Malaria Journal

ISSN: 1475-2875

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-01A-B82

DOI: 10.1186/s12936-025-05450-2

Abstract (EN): Malaria, a potentially fatal infectious disease, remains a significant global health concern, mainly in tropical regions. In Europe, its incidence is currently low and predominantly travel-related. Thus, a timely diagnosis requires healthcare teams to consider malaria in their differential diagnoses and obtain a thorough travel history. In medical laboratories, despite the present low case numbers, professionals must maintain a high diagnostic proficiency through continuous training and adherence to quality assurance programmes. First-line anti-malarial treatment with artemisinin derivatives is highly effective when implemented in a timely manner. However, as a consequence of their efficacy, a predictable haemolytic phenomenon may occur in some cases, which may be difficult to distinguish from manifestations of the disease itself. This mini review examines a case of travel-associated malaria to highlight diagnostic challenges from a medical laboratory perspective, with a particular focus on post-artesunate delayed haemolysis (PADH), a rare but potentially severe complication of malaria treatment.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7