Spread of new variant RHDV in domestic rabbits on the Iberian Peninsula

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Dalton, KP (Autor) Outra; Nicieza, I (Autor) Outra; Abrantes, J (Autor) Outra; Esteves, PJ (Autor) FCUP; Parra, F (Autor) Outra

Revista

Título: Veterinary Microbiology

Vol. 169

Páginas: 67-73

ISSN: 0378-1135

Editora: Elsevier

Indexação

ISI Web of Knowledge - 86 Citações

Scopus - 89 Citações

Outras Informações

ID Authenticus: P-009-761

DOI: 10.1016/j.vetmic.2013.12.015

Abstract (EN): Rabbit hemorrhagic disease outbreaks in young rabbits have been recently observed in Spain. In this study we have tracked the spread of variant RHDV in samples collected from rabbit farms over a period of more than one year using RT-PCR and antigen-capture ELISA. The isolates were sequenced and compared to classic and variant RHDV strains and phylogenetic analyses were conducted. Mortalities have been observed in kits as young as 11 days. More than 50% of the dead rabbits had been previously vaccinated against RHDV using commercially available inactivated vaccines indicating a putative lack of protection against the variant RHDV. The large majority of the studied outbreaks (94.5%) in Spanish farms during 2012 were due to variant RHDV and only 3 out of the 55 farms were affected by classic RHDV. The data demonstrates that the variant RHDV has spread through a large number of Spanish provinces in a relatively short period of time, largely replacing the previously predominant G1 RHDV genotypes. Considering the lack of efficient vaccines against the variant RHDV strains strict disease control and greater vigilance measures should be put in place.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7