Blood pressure response to mineralocorticoid receptor antagonists or aldosterone synthase inhibitors according to baseline renin levels

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2025

Autores

Leite, AR (Autor) Outra; Angelico-Gonçalves, A (Autor) Outra; Leite-Moreira AF (Autor) FMUP; Neves, JS (Autor) Outra; Ferreira, JP (Autor) Outra

Revista

Título: Journal of Human Hypertension

Vol. 39

Páginas: 462-464

ISSN: 0950-9240

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-018-SFA

DOI: 10.1038/s41371-025-01021-9

Abstract (EN): Plasma renin is a surrogate marker of sodium retention in hypertension, and its levels are suppressed in conditions of heightened aldosterone production. We performed a random-effects meta-analysis of randomized clinical trials focusing on the impact of mineralocorticoid receptor antagonists (MRA) and aldosterone synthase inhibitors (ASi) on blood pressure according to baseline renin levels. We included four randomized clinical trials, and we found that the response to MRA or ASi was independent of baseline plasma renin levels.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3