Spleen-Restricted Posttransplant Lymphoproliferative Disorder in the First Year After Kidney Transplant - A Case Report

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2022

Autores

Rodrigues, AC (Autor) Outra; Fernandes, S (Autor) Outra; Bustorff, M (Autor) Outra; Nunes, AT (Autor) Outra; Ferreira, I (Autor) Outra; Tavares, I (Autor) FMUP; Rocha, A (Autor) Outra; Carneiro, A (Autor) Outra; Sampaio, SN (Autor) Outra

Revista

Título: Transplantation Proceedings

ISSN: 0041-1345

Editora: Elsevier

Indexação

ISI Web of Knowledge - 1 Citação

Scopus - 1 Citação

Outras Informações

ID Authenticus: P-00W-KBE

DOI: 10.1016/j.transproceed.2022.03.005

Abstract (EN): Posttransplant lymphoproliferative disorders (PTLDs) are a feared complication after transplant. They are mostly of B cell origin and are frequently Epstein-Barr virus (EBV)-positive, particu-larly in early onset PTLD. Later on, non-B and EBV-negative PTLD are increasingly reported. EBV seronegative receptors (particularly when paired with an EBV seropositive donor) together with the net degree of immunosuppression-a concept often difficult to quantify-are the most consistently described risk factors for the development of PTLD. Conversely, its association with a particular immunosuppressive agent or other virus, namely cytomegalovirus (CMV) infec-tion or disease, has been inconsistently reported. We present a challenging case where an EBV negative monomorphic peripheric T-cell lymphoma was diagnosed in the first year after kidney in a with a recent of CMV disease from a resistant strain.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3