Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2021

Autores

Araujo, AM (Autor) Outra; Felix Carvalho (Autor) FFUP; de Pinho, PG (Autor) FFUP; Carvalho, M (Autor) FFUP

Revista

Título: Metabolites

Vol. 11

Página Final: 692

ISSN: 2218-1989

Editora: MDPI

Indexação

ISI Web of Knowledge - 34 Citações

Scopus - 37 Citações

Outras Informações

ID Authenticus: P-00V-MDQ

DOI: 10.3390/metabo11100692

Abstract (EN): Given the high biological impact of classical and emerging toxicants, a sensitive and comprehensive assessment of the hazards and risks of these substances to organisms is urgently needed. In this sense, toxicometabolomics emerged as a new and growing field in life sciences, which use metabolomics to provide new sets of susceptibility, exposure, and/or effects biomarkers; and to characterize in detail the metabolic responses and altered biological pathways that various stressful stimuli cause in many organisms. The present review focuses on the analytical platforms and the typical workflow employed in toxicometabolomic studies, and gives an overview of recent exploratory research that applied metabolomics in various areas of toxicology.</p>

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 31