Nome: | Maria Helena da Silva de Vasconcelos Meehan |
Sigla: | MHSVM |
Estado: | Ativo |
R-000-BJ9 | |
0000-0002-7801-4643 | |
7006465065 |
Telefone: | 220428590 |
Extensão Telefónica: | 8590 |
Salas: | E3 | S26.P5.E3 |
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Cargo | Data de Início |
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Membro da Comissão de Acompanhamento de Curso - Doutoramento em Ciências Farmacêuticas | 2025-02-03 |
Helena's current research focuses on the identification and validation of biomarkers and therapeutic targets to overcome drug resistance in cancer. She has been focusing on studying Extracellular Vesicles as a source of biomarkers of drug resistance and their role in the intercellular communication between tumour cells and between those cells and the tumour microenvironment. In addition, she studies the activity of approved drugs and novel small molecules to counteract drug resistance mechanisms. Her work has led to the validation of therapeutic targets and the identification of "hit" small molecules.
Helena has been the PI of several research grants and has also served as referee of research projects for both national and international funding agencies. She has been a member of numerous scientific and organizing committees of national and international Meetings, Conferences and Workshops. She is also an Editor of the journals "Cancers" and "Molecules". Helena has also been a Management Committee Substitute Member of COST Action BM1202 “European Network on Microvesicles and Exosomes in Health and Disease”. She was Work Group Leader, and Management Committee Member, of COST Action CA17104 “New diagnostic and therapeutic tools against multidrug resistance tumors”. She was member of the Team, as Academic Consultant, of a COST Innovators Grant “Pan-European Educational Platform on Multidrug Resistant Tumours and Personalised Cancer Treatment - PANDORA". Helena was a founding member of “Associação PNEV - Portuguese Network on Extracellular Vesicles”.
She has supervised or co-supervised 12 PhD students who have completed their degree and is currently supervising/co-supervising another 6 PhD students. She has supervised or co-supervised 25 MSc students and is currently supervising/co-supervising a further 2 MSc students. Helena has also guided 4 hired researchers at post-doctoral level, 7 researchers with post-doctoral grants and has trained numerous young researchers with initiation to research grants (BIs) or technician grants (BTI). She has published 5 book chapters and more than 130 peer-reviewed papers in international prestigious journals such as Drug Resistance Updates, Sci Reports, ACS Nano, BBA, Autophagy, Cancer Letters, Int J Cancer, Eur J Cancer, Eur J Med Chem or Int J Pharm, Cancers, having an h-index of 44.
Researcher ID: J-9547-2013; Scopus Author ID: 7006465065
Link to research group: https://www.i3s.up.pt/research-group?x=8