Organic Chemistry II

Code:

MI071209

Acronym:

QORG2

Keywords
Classification	Keyword
OFICIAL	Physical Sciences

Instance: 2019/2020 - 2S

Active?	Yes
Responsible unit:	Organic and Pharmaceutical Chemistry Laboratory
Course/CS Responsible:	MSc in Pharmaceutical Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MICF	438	Official Curriculum	1	-	6	65	162

Teaching language

Suitable for English-speaking students

Objectives

a) Understanding the behaviour of carbon compounds and the modulation of this behaviour by the introduction of chemical functions. Systematisation of the different families of organic compounds and their associated behaviour. Relationship between the different organic families. Understanding the importance of tri-dimensionality of organic structures. Understanding the existence of the structure – chemical behaviour relationship. Chemicals synthesis, reactivity and characteristic reactions of several families of organic compounds. Acquisition of basic experimental methodology used in clarifying structure, either by chemical or spectrometric means. Evolution of student competence in the laboratory, developing good practices in the use of material and equipment while at the same time acquiring a greater awareness of laboratory safety rules. b) A basic knowledge of Organic Chemistry from the Organic Chemistry I subject is assumed. The presence and constant revision of this knowledge during the Organic Chemistry II subject is recommended.

Learning outcomes and competences

To understand and to predict the behavior of organic substances: their reactivity, synthesis, physicochemical characteristics. Given the structure of a substance, knowing to predict the UV, IR, NMR and MS spectra characteristics. Given the UV, IR, NMR and MS spectra of a substance, knowing to propose compatible structures.

To propose a protocol leading to the identification of an unknown substance.

Autonomy in the implementation of organic chemistry laboratory protocols (assessment of purity, purification, and identification of unknown pure substances and chemical extraction).

Working method

Presencial

Program

Systematic identification of organic compounds. Application of the spectrometric methods in structural determination, with special relevance to spectrophotometry in UV, IR, NMR and MS. Detection and confirmation of functional groups by chemical and spectral based methods. Study of functional organic compounds (alcohols, thiols, ethers, aldehydes and ketones, carboxylic acids and derivatives, enols, phenols, alkylamines and arylamines): nomenclature, physical - chemical properties, spectroscopic properties, preparation processes, properties and reactivity and mechanisms. Resolution of mixtures by chemical means.

Mandatory literature

McMurry John; Organic chemistry. ISBN: 0-534-42005-2
Shriner Ralph L. 070; systematic identification of organic compounds. ISBN: 0-471-21503-1
Ault Addison; Techniques and experiments for organic chemistry. ISBN: 0-205-06528-7
Vollhardt K. Peter C.; Organic chemistry: structure and function. ISBN: 0-7167-2721-8
Solomons T. W. Graham; Organic chemistry. ISBN: 0-471-03594-7
J. Pasto Daniel; Determinación de estructuras orgánicas
Pecsok Robert L.; Métodos modernos de análisis químico
Pinto Madalena M. M. 340; Manual de trabalhos laboratoriais de química orgânica e farmacêutica. ISBN: 978-972-757-750-7

Teaching methods and learning activities

a) Theoretical classes (3 hours / week): Powerpoint presentations; associating the subject-matters taught with information and curiosities on the work of the chemicals discussed in the class and the way those subject-matters are related to day to day life. b) The laboratory work (2 hours / week, 12 weeks) is carried out in groups of 2 to 3 students according to a chronogram. The logic behind this and the objectives to attain are previously made known to the students. The lecturer responsible is available for student consultation at the hours specified in the beginning of the semester and by prior agreed appointment at any other time. c) The students are involved in bibliographical research tasks covering themes related to the subject-matters taught and their application. This work is on-going and is discussed with the participants over the semester. The professors involved in the theoretical and laboratorial classes are available to discuss any doubts raised by the students either by direct contact in the scheduled period made known to students at the beginning of the semester or by email contact.

Software

ChemOffice
ChemSpider (http://www.chemspider.com/)
SynArchive (http://www.synarchive.com/)
ACD/I-Lab (https://ilab.acdlabs.com/iLab2/)

keywords

Physical sciences > Chemistry > Organic chemistry > Quimica do carbono

Evaluation Type

Distributed evaluation without final exam

Assessment Components

designation	Weight (%)
Exame	80,00
Trabalho laboratorial	20,00
Total:	100,00

Amount of time allocated to each course unit

designation	Time (hours)
Estudo autónomo	50,00
Frequência das aulas	50,00
Total:	100,00

Eligibility for exams

- Student attendance to the Laboratory classes is mandatory. Those students whose attendance is lower than 3/4 of the classes effectively taught are considered as without attendance, as long as these classes represent more than 50% of the classes predicted. Nevertheless, at the end of the classes period the student must have performed all the laboratorial tasks foreseen in the laboratorial program. - Attendance to Theoretical classes is not compulsory.

Calculation formula of final grade

The evaluation of the discipline for the students who attend the laboratory classes will include the following components:

- Performance, discipline follow-up, reports (10%);
- "A nossa molécula" (10%);
- 1st evaluation test (40%);
- 2nd evaluation test (40%).

In order for the other components of the evaluation to be considered, the student must obtain 9.5 values ​​in the weighted set of the two frequencies.
Who does not reach 9.5 values should take final exam (80% of the final grade).
Frequencies are mandatory, including student-workers.

 

The evaluation of the discipline for students who have already obtained the frequency of the curricular unit in previous years:
- 1st evaluation test (50%)
- 2nd evaluation test (50%)

In the weighted set of the 2 frequencies students must obtain 9.5 values.
Who does not reach 9.5 values should take final exam (100% of the final grade).
Frequencies are mandatory, including student-workers.

Examinations or Special Assignments

Laboratorial evaluation: performance, comprehension of the taught contents and reports. Intermediate written test devoted to assess the students learning status regarding both the theoretical and laboratorial contents. The work "A nossa molécula" will be developed during the semester. This work will be delivered in the moodle platform and in paper support for presentation and discussion with FFUP teachers at the end of the semester. The first test involves the concepts related to the laboratory works and the contents taught up to that point in the theoretical classes. Thesecond test will focus preferentially on the subjects discussed in the classes given after the interim test, but the integration of all the knowledge acquired during the semester can not be forgotten.

Special assessment (TE, DA, ...)

The legal approved "Normas de Avaliação” are applied. The exams for the special regime students are carried out in accordance with that established in the applicable legislation for each specific situation.

Classification improvement

The legal approved "Normas de Avaliação” are applied. - The student has the right to request the repeat of the final test to improve the mark in the in one of the normal or resource period of the following academic year in which he/she carried out the test . - The repeat of the tests to improve the mark can be undertaken only once per subject. - The final subject classification will be the higher of those obtained in the two tests carried out. The classification improvement in Química Orgânica II is obtained through a written exam including all contents taught in the subject, both theoretical and laboratorial.

Observations

The evaluation of the discipline for students who attended laboratory classes will include the following components:



- Performance, discipline follow-up, reports (0.5 / 20 points);

- "A Nossa Molécula" (5.5 / 20 values);

- 1st evaluation test (7/20 values);

- 2nd evaluation test (7/20 values). 

For the other components of the assessment to be considered,
 the student must obtain a positive assessment in the 
weighted set of the two evaluations, that is, considering 
each frequency valued at 20 points, the student must obtain
 at least 9.5 points in the average of the two frequencies.
 
Those who do not reach 9.5 values must take the final exam
 at "Época de Recurso" (14/20 points of the final grade). 
The evaluation tests are mandatory, including for student
workers. 
The evaluation of the discipline for students who have 
already obtained the frequency of the course in 
previous years will include the following components:
 - 1st Frequency (10/20 points) 
- 2nd Frequency (10/20 points) 

In the weighted set of the 2 tests, students should obtain
 9.5 values. Those who do not reach 9.5 values ​​must take 
the final exam at "Época de Recurso" (100% of the final
 grade). Frequencies are mandatory, including for 
student workers. 
Students with an average of 2 tests between 8.5 and 9.4 
will be able to take an oral exam to obtain the necessary 
positive grade. Students with a grade higher than 16.9 in 
the average of the 2 frequencies, must take an oral test, 
otherwise the grade of 16.9 will be valid.