Haematology

Code:

MI074133

Acronym:

HEMATO

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2013/2014 - 1S

Active?	Yes
Responsible unit:	Biochemistry Laboratory
Course/CS Responsible:	MSc in Pharmaceutical Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MICF	224	Official Curriculum	4	-	5,5	52	148,5

Teaching language

Portuguese

Objectives

 

The aim of the teoric component of these studies is to prepare the students with a solid basis in hematology, giving a particular emphasis in the most prevalent hematologic disorders in Portugal.

 

The laboratorial component, strongly linked to the teoric component, prepares the student to  perform the hematological studies needed to the first aproach to an hematological patient and to its correct reading and interpretation. It is important for a pharmacist the knowledge of the medicines used in hematological disorders and the laboratorial assays used for their diagnosis and monitoring.

 

Learning outcomes and competences

 

The laboratorial component, strongly linked to the teoric component, prepares the student to  perform the hematological studies needed to the first aproach to an hematological patient and to its correct reading and interpretation. It is important for a pharmacist the knowledge of the medicines used in hematological disorders and the laboratorial assays used for their diagnosis and monitoring.

 

Working method

Presencial

Program

 

Hematopoiesis.

Collection of blood and bone marrow

The erythrocyte – morphology, structure, membrane and cytoplasm constituents, metabolism, aging and removal

Anemia. Iron deficiency anemia, sideroblastic anemia, anemia of chronic disorders, megaloblastic anemia, hemolytic anemia, talassemia and other hemoglobinopathies.

The white cells and their benign disorders

Blood group systems – ABO and Rhesus. Aloimmunization in blood transfusion and pregnancy.

Blood transfusion. Blood donor and recipiente

Hemostasis. Laboratorial tests to study hemostatic function

Hematological malignancies

Acute myeloid leukemia and acute lymphoblastic leukemia

Myelodisplastic syndromes

Myeloproliferative disorders. Chronic myeloid leukemia

The chronic lymphoid leukemias

Lymphomas

 

Basic hematological study. Reticulocyte count. Cases of anemia and leukocyte benign disorders. Identification of hematopoietic precursors in bone marrow and peripheral blood smears. Evaluation of ABO and Rhesus blood group.

 

Mandatory literature

Hoffbrand A. V.; Essential haematology. ISBN: 0-632-05153-1
Hillman Robert S.; Hematology in clinical practice: a guide to diagnosis and management. ISBN: 0-07-137502-3

Complementary Bibliography

Hoffbrand Victor A.; Color atlas of clinical hematology. ISBN: 0-7234-3115-9
Hoffbrand A. Victor 340; Postgraduate haematology. ISBN: 1-405-10821-5
Beutler Ernest 340; Williams hematology. ISBN: 0-07-116293-3
Dacie J. V.; Practical Haematology. ISBN: 0 443 01262 8
Williams William J.; Hematology. ISBN: 0-07-070377-9
Lewis S. Mitchell ed.; Dacie and Lewis practical haematology. ISBN: 0-443-06377-X
Lee G. Richard; Wintrobe.s clinical hematology. ISBN: 0-8121-1188-5

Teaching methods and learning activities

 

Tutorial classes: supported by projection of ilustrating slides

Laboratorial classes: each student perform the experiments described in the laboratorial program. Presentation and discussion of clinical cases

Type of evaluation: Final exam

Attendance to the tutorial classes is not compulsory.

Formula Evaluation: The laboratorial evaluation takes place in the last laboratorial class and may include any of the assays performed along the laboratorial classes. The student must have 9.5 out of 20 to be admitted to the final laboratorial exam, in which the minimum mark is 9.5; Aproved in this laboratorial component, the student is admitted to the final written teoric exam, covering all the issues addressed in laboratorial and teoric classes. The student must have 9.5 out of 20 to be approved.

 

Evaluation Type

Distributed evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	80,00
Trabalho laboratorial	20,00
Total:	100,00

Calculation formula of final grade

 

The final note will be calculated according to:

80% of the mark from the teoric exam+ 20% of themark of the laboratorial exam