Pharmaceutical Technology III

Code:

MI073228

Acronym:

TF3-3

Keywords
Classification	Keyword
OFICIAL	Technological Sciences

Instance: 2013/2014 - 2S

Active?	Yes
Web Page:	https://moodle.up.pt/course/view.php?id=119
Responsible unit:	Pharmaceutical Technology Laboratory
Course/CS Responsible:	MSc in Pharmaceutical Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MICF	212	Official Curriculum	3	-	5,5	52	148,5

Teaching language

Portuguese

Objectives

Aims:
To integrate and apply by the students’, knowledge acquired in Course Units propaedeutic and in the two Pharmaceutical Technologies previously taught.
Acquire knowledge that enables them to formulate, prepare and ensure the quality of skin preparations, rectal, vaginal, oromucosal and aerosols.
To know the process of industrial production for the group of the semisolids preparations for skin application and preparations for applying in vaginal, rectal and oromucosal mucous membranes.
To know the process for the production of aerosols and the varieties of forms existing on the market.

To achieve these goals, the student must apply 148.5 h (5.5 ECTS x 27 h), of which 26 h correspond to lectures and 22h to laboratory classes. Of the remaining 100.5 h, circa 4h will correspond to the evaluation and the remaining 96.5 h correspond to the work/study time.

Learning outcomes and competences

Learning outcomes:
In the end, students should master the terminology and concepts used in Pharmaceutical Technology and the technical and scientific aspects inherent to drugs, in particular those relating to skin preparations, rectal, vaginal, oromucosal and aerosols – ointments, creams gels, pastes, suppositories, etc.

Skills:
Learn to formulate and prepare, from the industrial point of view and officinal compounding:
1 - cutaneous, vaginal, rectal and oromucosal medicines
Learn to formulate and prepare from the industrial point of view:
2 – medicated aerosol.

Working method

Presencial

Program

I. Pharmaceutical forms for application in skin

1. Introduction
2. Semisolid preparations

2.1 Official classification and other classifications
2.2 General and specific characteristics of preparations
2.3 Excipients
2.4 Preparation methodologies
2.5 Packaging, labeling and conservation
2.6 Quality control

3. Other preparations for dermal application

3.1 Liquid preparations
3.2 Solid preparations

II- Pharmaceutical forms for application on mucous membranes

1. Rectal and vaginal preparations

1.1 Categories
1.2 Excipients
1.3 Production
1.4 Quality control

2. Oromucosal and other preparations

2.1 Categories
2.2 Excipients
2.3 Production
2.4 Quality control

III – Aerosol systems

1. History and the foundation of the aerosol system

1.1 Types of aerosols and applications

2 Pressurized pharmaceutical preparations

2.1 Essential parts of preparations and respective function
2.2 Propellants
2.3 Production
2.4 Quality control

Mandatory literature

Prista L. Nogueira; Tecnologia farmacêutica. ISBN: 978-972-31-0975-7
Comissão da Farmacopeia Portuguesa; Farmacopeia portuguesa VIII. ISBN: 972-8425-67-8
American Pharmaceutical Association; Handbook of pharmaceutical excipients. ISBN: 0-85369-164-9
Gerbino Philip 300; Remington: the science and practice of pharmacy. ISBN: 0-7817-4673-6

Teaching methods and learning activities

Lecture and laboratory classes. E-learning.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	65,00
Trabalho laboratorial	35,00
Total:	100,00

Eligibility for exams

According to the standards of the Pedagogical Council.

Calculation formula of final grade

EVALUATION METHOD
The evaluation method of discipline follows the assessment Standards for the school year approved by the Pedagogical Council, to which it adds the following:

1-LABORATORY ASSESSMENT
1.1- Laboratory evaluation components

a) Evaluation during laboratory classes - During each of these classes, questions will be asked to an element of each group. At the end of each lesson, each group presents a written report of each of the works performed.
b) Realization of a random work - After conducting laboratory classes, students are subjected to a laboratory evaluation that consists in the realization of a random work about a pharmaceutical dosage form and a written report.
Each student will be assigned a classification for the work done (if the rank is less than 9.5 values students will have to perform the final laboratory exam).

1.2- Laboratory classification

The laboratory classification results from the weighted average of the components of laboratory evaluation a) and b) which correspond, respectively, to 15%, and 20% of the total value of the final mark.

1.3-Final laboratory exam

Students whose laboratory continuous classification exceeds 9.5 values are exempted from carrying out a final laboratory examination and may present itself automatically to the final theory exam.
The final laboratory exam will be held on the date fixed by the Pedagogical Council.

2-FINAL THEORY EXAM

The final written exam will be held on the date fixed by the Pedagogical Council. The students who have rank equal to or greater than 9.5 are approved. The students who have rank less than 9.5 are disapproved.

3-ORAL EXAM

Students who have obtained rating equal to or greater than 9.5 may request oral exam. The petition will be delivered to the SGAE until 48 hours after the publication of the notes.

4-FINAL CLASSIFICATION

Relative weight of laboratory evaluation in the final classification – 35%
Relative weight of theoretical classification in the final classification – 65%
If the student makes the oral exam, the classification results only from the oral exam, which will focus on the laboratory and theoretical matters.