Organic Chemistry I

Code:

MI071101

Acronym:

QORG1

Keywords
Classification	Keyword
OFICIAL	Physical Sciences

Instance: 2012/2013 - 1S

Active?	Yes
Responsible unit:	Organic and Pharmaceutical Chemistry Laboratory
Course/CS Responsible:	MSc in Pharmaceutical Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MICF	328	Official Curriculum	1	-	6	65	162

Teaching language

Portuguese

Objectives

Understanding the behaviour of organic compounds concerning the relationship of chemical structure with the respective physical-chemistry and reactivity properties. Understanding the importance of the tri-dimensionality of organic structures.

Implementation of the rules concerning laboratory safety and good practices in the use of materials and equipment. Learning to apply the basic techniques of obtention, isolation, purification and purity control in samples of diverse origin.

Program

Study of organic compounds: alkanes, cyclic alkanes, haloalkanes, alkenes, alkynes, alkyl halides and aromatic compounds: Structures, nomenclature, physical-chemical properties, synthesis and reactivity, mechanisms. Conformational analysis. Stereochemistry: chiral compounds, optical activity, separation of enantiomers; stereochemistry in chemical reactions.
Execution of laboratory tasks aimed at the basic operations for the separation, purification and control of purity of organic compounds.

Mandatory literature

Ault Addison; Techniques and experiments for organic chemistry. ISBN: 0-935702-76-8
Marmor Solomon; Laboratory methods in organic chemistry. ISBN: 0-8087-3997-2
Vollhardt K. Peter C.; Organic chemistry: structure and function. ISBN: 0-7167-4374-4
McMurry John; Organic chemistry. ISBN: 978-0-495-11628-8
Sykes Peter; Estudo dos mecanismos das reacções orgânicas
McMurry Susan; Study guide and solutions manual for McMurry.s organic chemistry. ISBN: 978-0-495-11268-6
Tomé Augusto; Introdução à nomenclatura de compostos orgânicos. ISBN: 978-972-592-278-1
Madalena M M Pinto e cols.; Manual de Trabalhos laboratoriais de Química Orgânica e Farmacêutica, Lidel, 2011. ISBN: 978-972-757-750-7

Teaching methods and learning activities

Theoretical classes (3 hours/week): Powerpoint and “blackboard” presentations.
The subject-matters will be always linked with day to day life and pharmaceutical sciences and is intended to supply propedeutic bases for other subjects. The discussion on the theme and the resolution of related questions is encouraged at the end of each chapter.

laboratorial classes
Following discussion classes on the background of methods (1 week) and a laboratorial demonstration class (1 week), the laboratory work (2 hours / week) is carried out in groups of 2 to 3 students on a rotary basis and according to a chronogram.

The lecturers responsible are available for student consultation at the hours specified in the beginning of the semester and by prior, agreed appointment at any other time.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Attendance (estimated)	Participação presencial	65,00
	Total:	-	0,00

Eligibility for exams

- Attendance to theoretical classes is not compulsory.
- During classes the students will be evaluated by a written test, involving laboratorial matters. The performance of this is compulsory.
- Student attendance to the laboratorial classes is mandatory.
- For admission to the final theoretical exam the students should have a laboratorial final classification higher than 10. Students with a laboratorial final classification lower than 10 will be submitted to a laboratorial exam.

Calculation formula of final grade

- The final grade is attributed by the following manner: 75% from the written final exam, 25% from the laboratorial component. The laboratorial component involves the classification obtained in a written test and the performance of the students during laboratorial classes.
- Students with final grades equal or superior to 10 will be approved and with final grades inferior to 10 will be reproved.

Examinations or Special Assignments

During classes the students will be evaluated by a written test, involving laboratorial matters. The performance of this is compulsory.

Special assessment (TE, DA, ...)

The exams for the special regime students are carried out in accordance with that established in the applicable legislation for each specific situation.

Classification improvement

For classification improvement the student has to perform an writen final exam. The laboratorial grade will be mantained. The final grade is attributed by the following manner: 75% from the written final exam, 25% from the laboratorial component.

Observations

A basic knowledge of General Chemistry and Physical-Chemistry is assumed.