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Refractory neurogenic detrusor overactivity

Title
Refractory neurogenic detrusor overactivity
Type
Another Publication in an International Scientific Journal
Year
2006
Authors
Francisco Cruz
(Author)
FMUP
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Carlos Silva
(Author)
FMUP
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Journal
Vol. 60
Pages: 22-26
ISSN: 1368-5031
Publisher: Wiley-Blackwell
Indexing
Pubmed / Medline
Scientific classification
FOS: Medical and Health sciences > Clinical medicine
CORDIS: Health sciences > Medical sciences > Medicine > Urology
Other information
Authenticus ID: P-004-FQM
Abstract (EN): Refractory neurogenic detrusor overactivity refers to the clinical condition that is no longer manageable by anticholinergic therapy. This condition represents a formidable task to caregivers because the treatment of urinary incontinence and adequate protection of the upper urinary tract become extremely difficult. Treatment options for refractory neurogenic detrusor overactivity include detrusor injections of botulinum toxin and intravesical instillation of vanilloid compounds, mainly resiniferatoxin, or anticholinergic drugs. If these options fail, bladder augmentation or sacral anterior root stimulation offers excellent outcomes, although at much higher costs and risks to the patients.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 5
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