Childhood Obesity and Impact on the Kidney

• Type: Another Publication in an International Scientific Journal
• Date: 2019

Authors

Correia Costa, L (Author) Other; Azevedo A (Author) FMUP; Alberto Caldas Afonso (Author) ICBAS

Journal

Title: Nephron

Vol. 143

Pages: 8-11

ISSN: 1660-8151

Publisher: Karger

Indexing

ISI Web of Knowledge - 15 Citations

Scopus - 21 Citations

Other information

Authenticus ID: P-00P-TJJ

DOI: 10.1159/000492826

Abstract (EN): Obesity is known to be associated with a myriad of cardiovascular and metabolic comorbidities. In children, several longitudinal studies have shown that obesity consequences start early in life and accompany the obese child into adulthood, implying a higher risk of adverse cardiovascular events. More recently, data related to the possible role of obesity in the risk of kidney disease in adults, independently of diabetes, has started to become more available. In children, the evidence is scarcer, but it has also been acknowledged that obesity acts as a risk factor for disease progression when kidney impairment already exists, thereby increasing the risk of death among children with end-stage renal disease (ESRD). Besides this, there is also evidence that otherwise healthy overweight and obese children have a significant increase in the risk of all-cause ESRD later in life. The potential mechanisms underlying this association need to be further discussed in order to allow the setting in motion of preventive strategies to halt chronic kidney disease development and progression. (C) 2018 S. Karger AG, Basel

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4