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Methodological features of quantitative studies on medication adherence in older patients with chronic morbidity: A systematic review

Title
Methodological features of quantitative studies on medication adherence in older patients with chronic morbidity: A systematic review
Type
Another Publication in an International Scientific Journal
Year
2020
Authors
Granata, N
(Author)
Other
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Traversoni, S
(Author)
Other
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Kardas, P
(Author)
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Kurczewska Michalak, M
(Author)
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Costa, E
(Author)
FFUP
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Midao, L
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Giardini, A
(Author)
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Journal
Vol. 103
Pages: 2132-2141
ISSN: 0738-3991
Publisher: Elsevier
Other information
Authenticus ID: P-00S-3MX
Abstract (EN): Objectives: The growing number of chronic, multimorbid older adults encourages healthcare systems to cope with polypharmacy and non-adherence. However, methodology on how to provide effective interventions to enhance medication adherence is still object of debate. Methods: To describe methodological features of quantitative studies concerning older adults' medication adherence, by means of a PRISMA systematic review (Scopus, PubMed, Medline). A specific focus was devoted to theoretical models and to the ABC Taxonomy model, as stated by the EMERGE guidelines. Results: 55 papers were included. Most of the studies were conducted using randomized control trials (63.6%) and focused on a single disease only (72.7%). Most of the interventions were provided by a single professional figure (70.9%). Medication adherence was mainly evaluated by means of questionnaires (61.8%) and by clinical records (30.9%). Sixteen studies considered a theoretical model in the intervention framework. The Initiation phase (ABC Taxonomy) was the most neglected. Conclusions: Future studies upon medication adherence should account real-life challenges such as multimorbidity, polypharmacy and interdisciplinarity, analyzing adherence as a complex, holistic process. Practice implications: Theoretical models may be useful to enhance the soundness of the results, to ease their comparability, to calibrate tailored strategies and to plan patient-centered interventions. (C) 2020 Published by Elsevier B.V.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 10
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