Porous HA scaffolds for drug releasing

• Type: Another Publication in an International Scientific Journal
• Date: 2005

Authors

Queiroz, AC (Author) Other; Santos, JD (Author) FEUP; Monteiro, FJ (Author) FEUP

Indexing

ISI Web of Knowledge - 8 Citations

ISI Web of Science

Scopus - 7 Citations

Scientific classification

FOS: Engineering and technology > Materials engineering

Other information

Authenticus ID: P-000-58A

Abstract (EN): Dense and porous hydroxyapatite materials aimed at being used in controlled drug delivery, were characterised and studied in order to evaluate their ability to adsorb and release sodium ampicillin in a controlled manner, as a model for a drug delivery system, potentially applicable associated to surgery for the treatment of bone defects. These porous materials should also have adequate mechanical strength to withstand manipulation and sculpturing in surgery room. Adsorption and release profiles were obtained for a range of porous materials, leading to higher adsorption rates and more adequate release profiles than for dense materials.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4