Chitosan: An option for development of essential oil delivery systems for oral cavity care?

• Type: Another Publication in an International Scientific Journal
• Date: 2009

Authors

Andre Sao Pedro (Author) Other; Elaine Cabral Albuquerque (Author) Other; Domingos Ferreira (Author) FFUP; Bruno Sarmento (Author) Other

Journal

Title: Carbohydrate Polymers

Vol. 76

Pages: 501-508

ISSN: 0144-8617

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 91 Citations

Scopus - 112 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-003-K31

DOI: 10.1016/j.carbpol.2008.12.016

Abstract (EN): Microencapsulation of bioactive compounds has received increased attention in the last decade. Among the polymers used for developing microparticulated systems, chitosan has been widely cited. Obtained by deacetylation of chitin, chitosan is a natural, biodegradable, biocompatible and mucoadhesive polymer with permeability enhancement properties. These data justify its use for overcoming the reduced efficacy of conventional treatments of oral diseases. Various tests simulating the buccal environment have described controlled drug release profile and significant activity against buccal pathogens by chitosan microparticles entrapping antimicrobial agents. Considering the increasing microbial resistance to conventional antibiotics, essential oils have shown to be an important option against these pathogens. For sustained stability and prolonged release of essential oils from pharmaceutical formulations, some authors have studied the association of chitosan to them. This review disserts about the application of chitosan and essential oils on oral cavity care pointing out their association may be an interesting option.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8