Pathophysiology and Pharmacotherapy I

Code:

MI074236

Acronym:

FPFTE1

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2010/2011 - 2S

Active?	Yes
Web Page:	http://moodle.up.pt/course/view.php?id=1082
Responsible unit:	Pharmacology Laboratory
Course/CS Responsible:	MSc in Pharmaceutical Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MICF	189	Official Curriculum	4	-	5	52	135

Teaching language

Portuguese

Objectives

At the end, the student should (1) know the main pathophyisiological mechanisms of diseases, (2) learn the basic principals of the correspondent pharmacotherapy, (3) integrate the information in order to interpretate and apply to real cases, and (4) be able to follow the state-of.the-art.

Program

Design and development of new drugs. Pathology of different organs ans systems and their pharmacotherapy: main pathophysiological mechanisms of diseases and correspondent pharmacotherapy
1. Design and development of new drugs
2. Pathophysiology and pharmacotherapy of disorders of the gastrointestinal system
2.1. Alterations in gastrointestinal function (diarrhea and constipation)
2.2. Peptic ulcer
2.3. Gastroesophageal reflux disease
2.4. Inflammatory bowel disease (Crohn’s disease and ulcerative colitis)
3. Pathophysiology and pharmacotherapy of disorders of the respiratory system
3.1. Common viral respiratory infections and Influenza
3.2. Asthma
3.3. Chronic obstructive pulmonary disease
3.4. Sleep apnea
3.5. Infections of the upper respiratory tract
4. Pathophysiology and pharmacotherapy of disorders of the cardiovascular system
4.1. Arterial hypertension
4.2. ST-segment elevation myocardial infarction
4.3. Isquemic stroke
4.4. Venous thrombosis
4.5. Stable angina
5. Pathophysiology and pharmacotherapy of disorders of the osteoarticular system
5.1. Reumatic inflammatory diseases
5.2. Osteoporosis
5.3. Gout
5.4. Osteoarthritis of the knee
5.5. Psoriatic aryhritis
6. Pathophysiology and pharmacotherapy of psychiatric disorders
6.1. Mood disorders
6.2. Anxiety disorders
6.3. Schizophrenia
6.4. Panic disorder
6.5. Phobic disorders
6.6. Bipolar disorder

Mandatory literature

Herfindal Eric T. ed.; Clinical pharmacy and therapeutics. ISBN: 0-683-03963-6
Dipiro Joseph T. 340; Pharmacotherapy. ISBN: 0-07-136361-0
Guimarães Serafim; Terapêutica medicamentosa e suas bases farmacológicas. ISBN: 972-0-06029-8
Brunton Laurence L. 340; Goodman & Gilman. ISBN: 85-7726-001-1
Young Lloyd Y. ed.; Applied therapeutics: the clinical use of drugs. ISBN: 0-915486-09-1

Teaching methods and learning activities

Theaching is presencial complemented by the internet through the informatic network of the University if Porto and the e-learning platform Moodle. There will be 26 theorical (1h) and 13 pratical (2h) classes. Theorical classes will expose the most relevant features of each theme. Practical classes will allow exploring in more detail the pharmacotherapeutic approaches according to the more recent guidelines, exemplifying with clinical cases as ever as possible and discussing some thopics on students-prepared seminars.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Attendance (estimated)	Participação presencial	52,00
	Total:	-	0,00

Eligibility for exams

Evaluation of the course (20 points) will include the presentation and discussion of two small group-seminars (S) and the final exam (Ex). Participation of the students in the discussion of the clinical cases and seminars will also account for the evaluation. If the student miss one or the two seminar, the correspondent grade is 0. The final exam is a set of 50 multiple choice questions (75min total) on the programme. In order to pass, the student must have, at least, 10 (out of 20).

Calculation formula of final grade

Final classification = 30%*S + 70%*Ex.
Students with grades equal or above 10 are approved. Those with inferior grades must have a new evaluation. A bonus of 2 (out of 20) will be given accordingly to the participation on the discussion of the practical lessons.

Examinations or Special Assignments

None

Special assessment (TE, DA, ...)

As the rules of the Faculty. The CC part of the evaluation is also requires for those who are not obliged to attend the practical classes.

Classification improvement

Does not include the S part of the evaluation.

Observations

It is important that the student has at least basic knowledge of Anatomy, Histology, Physiology and Pharmacology.