Phytochemistry and Pharmacognosy I
Keywords |
Classification |
Keyword |
OFICIAL |
Physical Sciences |
Instance: 2012/2013 - 2S
Cycles of Study/Courses
Acronym |
No. of Students |
Study Plan |
Curricular Years |
Credits UCN |
Credits ECTS |
Contact hours |
Total Time |
MICF |
309 |
Official Curriculum |
2 |
- |
6 |
52 |
162 |
Teaching language
Portuguese
Objectives
Knowledge of basic metabolic pathways of plant biosynthesis (particularly acetate and shikimate pathway,);
Knowledge of chemical groups and biosynthetic pathways of origin of secondary metabolites;
Knowledge of drugs of natural origin, either included or not in pharmacopoeias:
-with pharmacological actions and used in therapeutics
-containing starting materials for the semisynthesis of pharmacologically active molecules by the pharmaceutical industry
- containing auxiliary substances for pharmaceutical and food industries.
Program
1. Concepts of phytochemistry and pharmacognosy
2. Therapeutic use of drugs of plant origin
3. Microscopic analysis of plant drugs
4. Primary metabolites
4.1. Carbohydrates
4.1.1. Monosaccharides
4.1.2. Oligosaccharides
4.1.3. Polysaccharides
4.1.3.1. Bacteria and fungi polysaccharides
4.1.3.2. Algae polysaccharides
4.1.3.3. Vascular plants polysaccharides
4.1.3.3.1. Homogeneous polysaccharides
4.1.3.3.1.1. Starch
4.1.3.3.1.2. Cellulose
4.1.3.3.1.3. Inulin
4.1.3.3.2. Heterogeneous polysaccharides
4.1.3.3.2.1. Gums
4.1.3.3.2.2. Mucilages
4.1.3.3.2.3. Pectic substances
5. Secondary metabolites
5.1. Acetyl-coenzyme A and acetate pathway metabolites
5.1.1. Quinones
5.1.1.1. Biosynthesis and classification
5.1.1.2. Physicochemical properties and analysis
5.1.1.3. Pharmacological activity and therapeutic use
5.1.1.4. Naphthoquinone-containing plant drugs
5.1.1.5. Anthraquinone-containing plant drugs
5.1.1.6. Naphthodiantrone-containing plant drugs
5.1.2. Orcinols
5.1.2.1. Biosynthesis
5.1.2.2. Pharmacological activity
5.1.2.3. Orcinol-containing plant drugs
5.2. Shikimic acid and shikimic acid pathway metabolites
5.2.1. Simple phenols and phenolic acids
5.2.1.1. Biosynthesis
5.2.1.2. Physicochemical properties and analysis
5.2.1.3. Simple phenol-containing plant drugs
5.2.1.4. Phenolic acid-containing plant drugs
5.2.2. Coumarins
5.2.2.1. Biosynthesis
5.2.2.2. Physicochemical properties and analysis
5.2.2.3. Pharmacological activity and therapeutic use
5.2.2.4. Coumarin-containing drugs
5.2.3. Lignans
5.2.3.1. Biosynthesis
5.2.3.2. Pharmacological activity and therapeutic use
5.2.3.3. Lignan-containing plant drugs
5.2.4. Diarylheptanoids, arylalkanones and stilbenoids
5.2.4.1. Biosynthesis
5.2.4.2. Physicochemical properties and analysis
5.2.4.3. Pharmacological activity and therapeutic use
5.2.4.4. Plant drugs containing diarylheptanoids, arylalkanones and stilbenoids
5.2.5. Xanthones
5.2.5.1. Biosynthesis
5.2.5.2. Physicochemical properties and analysis
5.2.5.3. Pharmacological activity and therapeutic use
5.2.5.4. Xanthone-containing plant drugs
5.2.6. Flavonoids
5.2.6.1. Biosynthesis, chemical structure and classification
5.2.6.2. Physicochemical properties and analysis
5.2.6.3. Biological properties and therapeutic use
5.2.6.3.1. Antioxidant activity
5.2.6.4. Flavonoid-containing drugs
5.2.7. Tannins
5.2.7.1. Biosynthesis, chemical structure and classification
5.2.7.2. Physicochemical properties and analysis
5.2.7.3. Biological properties and therapeutic use
5.2.7.4. Tannin containing drugs
Mandatory literature
Bruneton Jean;
Pharmacognosie, phytochimie, plantes médicinales. ISBN: 2-85206-911-3
Cunha A. Proença da 340;
Farmacognosia e fitoquímica. ISBN: 972-31-1142-X
Costa Aloísio Fernandes;
Farmacognosia. ISBN: 972-31-0913-1
Complementary Bibliography
Comissão da Farmacopeia Portuguesa;
Farmacopeia portuguesa VIII. ISBN: 972-8425-67-8
Teaching methods and learning activities
The course unit of Phytochemistry and Pharmacognosy I is included in the Moodle e-learning platform provided by the Office of Support for New Technologies in Education, UP. Thus, the presentations given in the lessons will be available in the platform. The platform also includes a forum to address the subjects from a different perspective of the lessons.
Theoretical lessons: 2 h/week. Presentations in "data show" (powerpoint software).
Laboratorial lessons: 2 h/week. In the beginning of the semester a laboratory handbook is supplied to the students, where they will find the protocols of the works to be performed and the respective theoretical explanation. Each laboratorial work will be carried out by groups of two students. Whenever possible, the laboratorial work will correspond to the content of the theoretical lectures, in order to facilitate their interconnection.
keywords
Social Sciences, Commerce and Law > Basic programmes
General programmes > Basic programmes
General programmes > Basic programmes > Basic programmes
General programmes > Basic programmes
Health sciences
Evaluation Type
Distributed evaluation with final exam
Assessment Components
Description |
Type |
Time (hours) |
Weight (%) |
End date |
Attendance (estimated) |
Participação presencial |
56,00 |
|
|
|
Total: |
- |
0,00 |
|
Eligibility for exams
The assistance of students to theoretical lectures is not mandatory.
The assistance of students to laboratory lectures is mandatory. Students with less than 75% attendance of effectively given lectures are considered not eligible for the exam.
Calculation formula of final grade
In the final classification, the laboratory component corresponds to 25%, with the remaining 75% allocated to the written test.
Students with a grade of less than 50% (2.5 points) of the value of the laboratory component in the evaluation of the course unit are considered failed and must perform a practical final exam.
Students who obtain a score on the written test less than 46.67% (7.0 points) of the value of the written component in the evaluation of the course unit are considered failed.
Examinations or Special Assignments
There is neither specific evaluation nor special assignments, except for those cases prescribed by law for students included in special regimens.
Special assessment (TE, DA, ...)
According to the general law and the rules adopted by the Educational Council.
Classification improvement
The improvement of classification consists of a practical test (optional) and a written test, covering all subjects taught in the lessons.
Observations
Prerequisites: knowledge of chemistry, including the distribution of chemical compounds by families and solubility characteristics of the compounds (acquired in the courses of General and Inorganic Chemistry, and Organic Chemistry I and II).