Sequence variation at three X chromosomal short tandem repeats in Caucasian and African populations

• Tipo: Artigo em Revista Científica Internacional
• Data: 2008

Autores

Gomes, I (Autor) Outra; Prinz, M (Autor) Outra; Pereira, R (Autor) Outra; Bieschke, E (Autor) Outra; Amorim, A (Autor) FCUP; Carracedo, A (Autor) Outra; Gusmao, L (Autor) Outra

Revista

Título: Forensic Science International: Genetics Supplement Series

Vol. 1 Nº 1

Páginas: 147-149

ISSN: 1875-1768

Editora: Elsevier

Indexação

ISI Web of Knowledge

Scopus - 2 Citações

Outras Informações

ID Authenticus: P-007-N2X

DOI: 10.1016/j.fsigss.2007.10.097

Abstract (EN): Sequence variation for the X chromosome short tandem repeats (X-STRs) DXS9898, DXS6789 and GATA172D05 was studied in two major population groups, namely Caucasians and Africans. DXS6789 revealed two different subtype sequence polymorphisms: for shorter alleles, with less than 17 repeats, results showed a simple composition with the following structure: (TATG)m-(TATC)n. For longer alleles, a constant TATC insertion was observed at the beginning of the variable repeat unit. Additionally, alleles identical in size revealed structural variations regarding the TATG/TATC proportion. Africans showed a higher intra-allelic variation at this locus than the Caucasian population group. For all three loci, DXS9898, DXS6789 and GATA172D05, no unique structure was found among Africans and Caucasians.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3