Population and mutation analysis of 17 Y-STR loci from Rio de Janeiro (Brazil)

• Tipo: Artigo em Revista Científica Internacional
• Data: 2005

Autores

Goes, ACD (Autor) Outra; de Carvalho, E (Autor) Outra; Gomes, I (Autor) Outra; da Silva, DA (Autor) Outra; Gil, SEF (Autor) Outra; Amorim, A (Autor) FCUP; Gusmao, L (Autor) Outra

Revista

Título: International Journal of Legal Medicine

Vol. 119

Páginas: 70-76

ISSN: 0937-9827

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 36 Citações

Scopus - 40 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Outras ciências médicas

Outras Informações

ID Authenticus: P-000-4GA

DOI: 10.1007/s00414-004-0504-x

Abstract (EN): The 17 Y chromosome STR loci DYS19, DYS385, DYS389I and II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS460, DYS461, GATA C4, GATA H4 and GATA A10 were analyzed in a male sample of 126 unrelated individuals from Rio de Janeiro. No shared haplotypes were observed, demonstrating the usefulness and informative power of these Y-STRs in male lineage identification in Rio de Janeiro. Pairwise haplotype analysis showed no significant differences in the comparison of Rio de Janeiro with Iberian samples from different regions of Portugal and Spain, as well as with other Caucasian samples from South America, namely Costa Rica, Buenos Aires (Argentina) and Sao Paulo (Brazil). The same set of Y-STRs was also typed in 119 father/son pairs and among 2,023 allele transfers, 8 mutations were observed with an overall mutation rate of 0.003955 +/- 0.001396 per locus/meiosis across the 17 loci. Except in one case, all mutations were single step. For DYS438 a four-step mutation was found which has never been reported before, where allele 10 mutated to allele 6.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7