Population and mutation analysis of 17 Y-STR loci from Rio de Janeiro (Brazil)

• Type: Article in International Scientific Journal
• Date: 2005

Authors

Goes, ACD (Author) Other; de Carvalho, E (Author) Other; Gomes, I (Author) Other; da Silva, DA (Author) Other; Gil, SEF (Author) Other; Amorim, A (Author) FCUP; Gusmao, L (Author) Other

Journal

Title: International Journal of Legal Medicine

Vol. 119

Pages: 70-76

ISSN: 0937-9827

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 36 Citations

Scopus - 40 Citations

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

Other information

Authenticus ID: P-000-4GA

DOI: 10.1007/s00414-004-0504-x

Abstract (EN): The 17 Y chromosome STR loci DYS19, DYS385, DYS389I and II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS460, DYS461, GATA C4, GATA H4 and GATA A10 were analyzed in a male sample of 126 unrelated individuals from Rio de Janeiro. No shared haplotypes were observed, demonstrating the usefulness and informative power of these Y-STRs in male lineage identification in Rio de Janeiro. Pairwise haplotype analysis showed no significant differences in the comparison of Rio de Janeiro with Iberian samples from different regions of Portugal and Spain, as well as with other Caucasian samples from South America, namely Costa Rica, Buenos Aires (Argentina) and Sao Paulo (Brazil). The same set of Y-STRs was also typed in 119 father/son pairs and among 2,023 allele transfers, 8 mutations were observed with an overall mutation rate of 0.003955 +/- 0.001396 per locus/meiosis across the 17 loci. Except in one case, all mutations were single step. For DYS438 a four-step mutation was found which has never been reported before, where allele 10 mutated to allele 6.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7