Population and segregation data on 17 Y-STRs: results of a GEP-ISFG collaborative study

• Tipo: Artigo em Revista Científica Internacional
• Data: 2008

Autores

Paula Sanchez Diz (Autor) Outra; Cintia Alves (Autor) Outra; Elizeu Carvalho (Autor) Outra; Monica Carvalho (Autor) Outra; Rosa Espinheira (Autor) Outra; Oscar Garcia (Autor) Outra; Fatima F Pinheiro (Autor) Outra; Lurdes Pontes (Autor) Outra; Joao J Porto (Autor) Outra; Oscar Santapa (Autor) Outra; Claudia Silva (Autor) Outra; Denilce Sumita (Autor) Outra; Sergio Valente (Autor) Outra; Martin Whittle (Autor) Outra; Inaki Yurrebaso (Autor) Outra; Angel Carracedo (Autor) Outra; Antonio Amorim (Autor) FCUP; Leonor Gusmao (Autor) Outra

Revista

Título: International Journal of Legal Medicine

Vol. 122

Páginas: 529-533

ISSN: 0937-9827

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 30 Citações

Scopus - 33 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Outras ciências médicas

Outras Informações

ID Authenticus: P-003-V5X

DOI: 10.1007/s00414-008-0265-z

Abstract (EN): A collaborative work was carried out by the Spanish and Portuguese International Society for Forensic Genetics Working Group in order to extend the existing data on Y-short tandem repeat (STR) mutations at the 17 Y chromosome STR loci included in the AmpFlSTR YFiler kit (Applied Biosystems): DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and GATA H4.1. In a sample of 701 father/son pairs, 26 mutations were observed among 11,917 allele transfers across the 17 loci. After summing previously reported mutation data with our sample, mutation rates varied between 4.25 x 10(-4) (95% CI 0.05 x 10(-3)-1.53 x 10(-3)) at DYS438 and 6.36 x 10(-3) (95% CI 2.75 x 10(-3)-12.49 x 10(-3)) at DYS458. All mutations were single step, and mutations in the same father/son pair were found twice.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5