Population and segregation data on 17 Y-STRs: results of a GEP-ISFG collaborative study

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Paula Sanchez Diz (Author) Other; Cintia Alves (Author) Other; Elizeu Carvalho (Author) Other; Monica Carvalho (Author) Other; Rosa Espinheira (Author) Other; Oscar Garcia (Author) Other; Fatima F Pinheiro (Author) Other; Lurdes Pontes (Author) Other; Joao J Porto (Author) Other; Oscar Santapa (Author) Other; Claudia Silva (Author) Other; Denilce Sumita (Author) Other; Sergio Valente (Author) Other; Martin Whittle (Author) Other; Inaki Yurrebaso (Author) Other; Angel Carracedo (Author) Other; Antonio Amorim (Author) FCUP; Leonor Gusmao (Author) Other

Journal

Title: International Journal of Legal Medicine

Vol. 122

Pages: 529-533

ISSN: 0937-9827

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 30 Citations

Scopus - 33 Citations

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

Other information

Authenticus ID: P-003-V5X

DOI: 10.1007/s00414-008-0265-z

Abstract (EN): A collaborative work was carried out by the Spanish and Portuguese International Society for Forensic Genetics Working Group in order to extend the existing data on Y-short tandem repeat (STR) mutations at the 17 Y chromosome STR loci included in the AmpFlSTR YFiler kit (Applied Biosystems): DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and GATA H4.1. In a sample of 701 father/son pairs, 26 mutations were observed among 11,917 allele transfers across the 17 loci. After summing previously reported mutation data with our sample, mutation rates varied between 4.25 x 10(-4) (95% CI 0.05 x 10(-3)-1.53 x 10(-3)) at DYS438 and 6.36 x 10(-3) (95% CI 2.75 x 10(-3)-12.49 x 10(-3)) at DYS458. All mutations were single step, and mutations in the same father/son pair were found twice.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5