Automatic analysis of macroarrays images

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2010

Autores

Caridade, CMR (Autor) Outra; Marcal, ARS (Autor) FCUP; Mendonca, T (Autor) FCUP; Albuquerque, P (Autor) Outra; Mendes, MV (Autor) Outra; Tavares, F (Autor) Outra

Ata de Conferência Internacional

Título: 2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)

Páginas: 6122-6125

32nd Annual International Conference of the IEEE Engineering-in-Medicine-and-Biology-Society (EMBC 10)

Buenos Aires, ARGENTINA, AUG 30-SEP 04, 2010

Indexação

ISI Web of Knowledge - 6 Citações

Scopus - 6 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Biotecnologia ambiental

Outras Informações

ID Authenticus: P-003-D8A

DOI: 10.1109/iembs.2010.5627805

Abstract (EN): The analysis of dot blot (macroarray) images is currently based on the human identification of positive/negative dots, which is a subjective and time consuming process. This paper presents a system for the automatic analysis of dot blot images, using a pre-defined grid of markers, including a number of ON and OFF controls. The geometric deformations of the input image are corrected, and the individual markers detected, both tasks fully automatically. Based on a previous training stage, the probability for each marker to be ON is established. This information is provided together with quality parameters for training, noise and classification, allowing for a fully automatic evaluation of a dot blot image.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4