Modeling anesthetic drugs' pharmacodynamic interaction on the Bispectral Index of the EEG: the influence of heart rate

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2007

Autores

Catarina S Nunes (Autor) FCUP; Teresa Mendonca (Autor) FCUP; Susana Bras (Autor) Outra; David A Ferreira (Autor) Outra; Pedro Amorim (Autor) Outra

Ata de Conferência Internacional

Título: PROCEEDINGS OF ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY

Páginas: 6480-6483

29th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society

Lyon, FRANCE, AUG 22-26, 2007

Indexação

ISI Web of Knowledge - 1 Citação

Scopus - 5 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Biotecnologia ambiental

Outras Informações

ID Authenticus: P-004-EZ3

DOI: 10.1109/iembs.2007.4353843

Abstract (EN): The effect of drugs' interaction on the brain signal Bispectral Index (BIS) is of great importance for an anesthesia control drug infusion system. In this study, the objective was to inspect the influence of patient's heart rate on the effect of the drugs on BIS. With this goal, the patient's heart rate was incorporated in an drug interaction model. The model was fitted per patient during anesthesia induction, and tested for prediction under surgery. The results showed that the model with time changing parameters incorporating patient's heart rate has a better performance than a non adjusted model. Three clusters of models were also identified using the fuzzy c-means algorithm. These clusters will help to distinguish between different patients' dynamics.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4