Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4

• Tipo: Artigo em Revista Científica Internacional
• Data: 2016

Autores

Mereiter, S (Autor) Outra; Magalhães, A (Autor) Outra; Adamczyk, B (Autor) Outra; Jin, C (Autor) Outra; Almeida, A (Autor) Outra; Drici, L (Autor) Outra; Ibáñez Vea, M (Autor) Outra; Larsen, MR (Autor) Outra; Kolarich, D (Autor) Outra; Karlsson, NG (Autor) Outra; Celso Reis (Autor) ICBAS

Revista

Título: Data in Brief

Vol. 7

Páginas: 814-833

ISSN: 2352-3409

Editora: Elsevier

Indexação

Scopus - 5 Citações

Outras Informações

ID Authenticus: P-00K-CM9

DOI: 10.1016/j.dib.2016.03.022

Abstract (EN): Gastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression. The N- and O-glycome data were generated in two parallel structural analyzes, based on PGC-ESI-MS/MS. Data on glycan structure identification and relative abundance in ST3GAL4 overexpressing cells and respective mock control are presented. The sialoproteomic analysis based on titanium-dioxide enrichment of sialopeptides with subsequent LC-MS/MS identification was performed. This analysis identified 47 proteins with significantly increased sialylation. The data in this article is associated with the research article published in Biochim Biophys Acta "Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer" [1]. © 2016 The Authors.

Idioma: Inglês

Tipo (Avaliação Docente): Científica