VITAMIN-B1 AND VITAMIN-B6 TUBULAR ELECTRODES AS FIA DETECTORS - THEIR USE IN THE ANALYSIS OF PHARMACEUTICAL PRODUCTS

• Tipo: Artigo em Revista Científica Internacional
• Data: 1991

Autores

LIMA, JLFC (Autor) FFUP; MONTENEGRO, MCBSM (Autor) FFUP; SILVA, AMR (Autor) Outra

Revista

Título: Journal of Pharmaceutical and Biomedical Analysis

Vol. 9

Páginas: 1041-1046

ISSN: 0731-7085

Editora: Elsevier

Indexação

ISI Web of Knowledge - 32 Citações

Scopus - 36 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-001-R66

DOI: 10.1016/0731-7085(91)80042-8

Abstract (EN): Ion-selective electrodes without an inner reference solution and tubular potentiometric detectors for the determination of vitamins B1 and B-6 in pharmaceutical preparations by flow injection analysis (FIA) are reported. The membranes were prepared with the vitamin tetra(2-chlorophenyl)borate (TCPB) dissolved in o-nitrophenyloctyl ether (o-NPOE) and immobilized on PVC. Intrinsic behaviour of the tubular detectors was assessed using a low-dispersion single-channel FIA manifold and was compared with conventionally-shaped electrodes using the same membrane. Data obtained in the determination of vitamins B1 and B-6 in pharmaceutical preparations with a double channel flow injection manifold incorporating the tubular detectors are presented and compared with those obtained by the U.S. Pharmacopeia method and by direct potentiometry with conventionally-shaped electrodes.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 6