Trimethoprim-selective electrodes with molecularly imprinted polymers acting as ionophores and potentiometric transduction on graphite solid-contact

• Tipo: Artigo em Revista Científica Internacional
• Data: 2011

Autores

Tania S C R Rebelo (Autor) Outra; Sofia A A Almeida (Autor) Outra; Rafaela R L Guerreiro (Autor) Outra; Conceicao C B S M Montenegro (Autor) FFUP; Goreti G F Sales (Autor) Outra

Revista

Título: Microchemical Journal

Vol. 98

Páginas: 21-28

ISSN: 0026-265X

Editora: Elsevier

Indexação

ISI Web of Knowledge - 20 Citações

Scopus - 25 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-002-S85

DOI: 10.1016/j.microc.2010.10.006

Abstract (EN): This work proposes a new biomimetic sensor material for trimethoprim. It is prepared by means of radical polymerization, having trimethylolpropane trimethacrylate as cross-linker, benzoyl peroxide as radicalar iniciator, chloroform as porogenic solvent, and methacrylic acid and 2-vinyl pyridine as monomers. Different percentages of sensor in a range between 1 and 6% were studied. Their behavior was compared to that obtained with ion-exchanger quaternary ammonium salt (additive tetrakis(p-chlorophenyl)borate or tetraphenylborate). The effect of an anionic additive in the sensing membrane was also tested. Trimethoprim sensors with 1% of imprinted particles from methacrylic acid monomers showed the best response in terms of slope (59.7 mV/decade) and detection limit (4.01 x 10(-7) mol/L). These electrodes displayed also a good selectivity towards nickel, manganese aluminium. ammonium, lead, potassium, sodium, iron, chromium, sulfadiazine, alanine, cysteine, tryptophan, valine and glycine. The sensors were not affected by pH changes from 2 to 6. They were successfully applied to the analysis of water from aquaculture.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8