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Environmental and Human Health Risks

Code: AMB4055     Acronym: AMB4055     Level: 400

Keywords
Classification Keyword
OFICIAL Environment

Instance: 2024/2025 - 2S Ícone do Moodle

Active? Yes
Responsible unit: Department of Geosciences, Environment and Spatial Plannings
Course/CS Responsible: Master in Geospatial Engineering

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
M:EGEO 0 Official Study Plan 1 - 6 42 162

Teaching Staff - Responsibilities

Teacher Responsibility
Ruth Maria de Oliveira Pereira

Teaching - Hours

Theoretical classes: 1,69
Theoretical and practical : 1,69
Type Teacher Classes Hour
Theoretical classes Totals 1 1,692
Ruth Maria de Oliveira Pereira 0,00
Anabela Ferreira De Oliveira Cachada 0,00
Theoretical and practical Totals 1 1,692
Ruth Maria de Oliveira Pereira 0,00
Anabela Ferreira De Oliveira Cachada 0,00

Teaching language

Portuguese and english

Objectives

With this curricular unit, it is intended that students achieve the following objectives:

  • They have a historical perspective on the evolution of risk assessment in the US and Europe.
  • Be able to distinguish predictive risk assessment from retrospective risk assessment, and understand the interconnection between these two processes
  • Understand the role of Ecotoxicology and Toxicology in producing information for risk assessment
  • Recognize the differences between the European and North American conceptual models of predictive risk assessment
  • Be able to use available tools to integrate toxicity data and derive PNECs (predicted no effect concentration)/risk limits for different chemical compounds
  • Be able to calculate risks to the environment by integrating chemical, ecotoxicological and ecological information, i.e. using TRIAD methodology and based on the weight of evidence
  • Understand what type of data can be collected to assess the hazard of a given substance
  • Understand the importance of using models in assessing risks to human health and the associated uncertainties
  • Be able to perform human health risk calculations for carcinogenic and non-carcinogenic compounds
  • Understand how quality criteria or reference values for soils are derived
  • Identify the main steps in retrospective risk assessment for human health and how this can also be carried out in stages
  • Understand the concept of bioavailability and bioaccessibility and what implications they could have on risk assessment

Learning outcomes and competences

At the end of this curricular unit, students will be able to:

  • Distinguish in which situations predictive or retrospective risk assessment schemes apply
  • Know the information they need to estimate risk limits (PNEC, HC5, RfD, etc.)
  • Use risk thresholds for retrospective risk assessment
  • Recognize the importance of ecotoxicological data for determining risk limits, using deterministic or probabilistic methods
  • Know how to use the main databases to collect information about the danger of a given substance and understand how this information was obtained
  • Identify the main steps of predictive and retrospective risk assessment for human health
  • Calculate human health risks for different types of compounds and interpret their results
  • Calculate quality criteria for soils
  • Distinguish the difference between total and available concentrations of a given substance in the soil

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

Do not exist.

Program


Module I) ASSESSMENT OF CHEMICAL RISKS TO THE ENVIRONMENT




a) Predictive risk assessment versus retrospective risk assessment and their link to current policies and regulations; b) Generic risk assessment scheme: exposure assessment, effects assessment and risk characterization; c) Conceptual model for environmental risk assessment proposed by USEPA; d) Conceptual model in tiers and in triad, proposed by the Netherlands; e) The integration of chemical, ecotoxicological and ecological information in the different stages of the risk assessment process; f) Deterministic (safety factors) and probabilistic (species sensitivity distribution curves) methods for determining risk limits (soil, water and sediment quality criteria); g) Models for calculating the risks of mixtures. h) Pesticide’s Risk Assessment.




Module II) ASSESSMENT OF CHEMICAL RISKS TO HUMAN HEALTH




a) Human health risk assessment model proposed by USEPA (IRIS) and the Netherlands; b) Data collection in the hazard assessment of substances; c) Dose-response curves with threshold and without threshold; d) Risk limits (tolerable daily intake and critical exposure limits) for human health to be used in calculating risks; e) Calculation of risks for non-carcinogenic compounds and for carcinogenic compounds; f) Calculation of quality criteria for soils; g) Concept of Bioavailability and bioaccessibility and methodologies for their assessment


Mandatory literature

Jensen, J., Mesman, M., Eds ; Ecological Risk Assessment of Contaminated Land. Decision Support for site specific investigations. RIVM report number 711701047, 2006. ISBN: 978-90-6960-138-0
Posthuma, L., Suter II, G.W., Traas, T.P. (eds), ; Species Sensitivity Distribution in Ecotoxicology, Lewis Publishers, 2002. ISBN: 1-56670-578-9
Robson, M.G., Toscano, W.A. (Eds); Risk assessment for environmental health, Jossey-Bass, 2007. ISBN: 0-7879-8319-5
Suter, G.W., Barnthouse, L.W., Bartell, S.M., Mill, T., Paterson, S., ; Ecological Risk Assessment of Contaminated Land. Decision Support for site specific investigations. RIVM report number 711701047, Lewis Publishers, 1993. ISBN: 9780873718752
Dannis J. Paustenbach; Human and Ecological Risk Assessment: Theory and Practice, Wiley Classics Library, 2002. ISBN: 0-471-14747-8
HELMUT GREIM and ROBERT SNYDER; Toxicology and Risk Assessment: A Comprehensive Introduction, John Wiley & Sons, Ltd, 2008
R.A. Fjeld, N.A. Eisenberg, K.L. Compton; Quantitative Environmental Risk Analysis for Human Health, Wiley Classics Library, 2007
R.A. Howd, A.M. Fan (Ed.); Risk Assessment for Chemicals in Drinking Water, Wiley Classics Library, 2008

Teaching methods and learning activities

Theoretical classes with frequent use of case studies, real data and updated bibliography published in specialized journals. Students will receive this bibliography to complement their study, along with the recommended bibliography.

In theoretical-practical classes, students will be able to use tools to support the calculation of risk limits and, using real data (from case studies in which teachers were involved), they will carry out risk calculations for the environment and human health. Role-play exercises will also be carried out in which students will be able to assume the roles of risk assessors and managers, in order to plan risk assessment processes for specific problem situations, making decisions about the necessary information and integrating it into the processes.

 

Evaluation Type

Distributed evaluation with final exam

Assessment Components

designation Weight (%)
Exame 40,00
Trabalho escrito 40,00
Apresentação/discussão de um trabalho científico 20,00
Total: 100,00

Amount of time allocated to each course unit

designation Time (hours)
Estudo autónomo 120,00
Frequência das aulas 42,00
Total: 162,00

Eligibility for exams

Attendance of classes as provided for in the FCUP statutes.

Calculation formula of final grade


The final assessment of the CU will be based on the following assignments:




A – Analysis and Presentation of a Scientific Article (20%)




B – Group work (40%)




C - Final exam (40%) (possible for grade improvement)




 




The final classification will be calculated based on the following equation:




Final Grade = A*0.2 + B* 0.40 + C x 0.40




Minimum final grade to be achieved for approval: 9.5 points (Scale: 0-20)




Minimum exam score: 4 points




This criterion applies to all examination periods.





 

Classification improvement

Only the exam grade can be improved at the appeal period

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