Genome, Transcriptome, and Proteome in Silico Analysis

Code:

B4002

Acronym:

B4002

Keywords
Classification	Keyword
OFICIAL	Biology

Instance: 2016/2017 - 2S

Active?	Yes
Responsible unit:	Department of Biology
Course/CS Responsible:	Master in Cell and Molecular Biology

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
M:BCM	20	Official Study Plan until 2023/2024	1	-	6	42	162

Teaching language

Portuguese

Objectives

Introduction and training in bioinformatics tools focusing on the user's standpoint. Case-studies in the context of ongoing research projects.

Learning outcomes and competences

Using diverse bioinformatics applications and resources in the context of specific problems. Training in data-mining, retriving of significant data from specific databases, integrating diverse bioinformatic tools in response to specific problems.

Working method

Presencial

Program

From basic in silico resources to more advanced bioinformatics applications.  Data-mining, Blast on NCBI, Multiple sequence alingment (Clustal on EBI), ORF finding, DNA sequences analysis and editing (MEGA), phylogenetic analysis.
Genome-analysis applied tools. Proteomics. Postranslation protein analysis and molecular modelling.

Mandatory literature

Albuquerque et al. ; DNA signature-based approaches for bacterial detection and identification, Elsevier, 2009

Teaching methods and learning activities

Presentation of Case studies in the context of ongoing research projects and practical training sessions in the computer lab.
Oral presentations and written reports. Final exam.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	90,00
Prova oral	10,00
Total:	100,00

Calculation formula of final grade

Final examination - 33% + written paper - 67%