Trimethoprim-selective electrodes with molecularly imprinted polymers acting as ionophores and potentiometric transduction on graphite solid-contact

• Type: Article in International Scientific Journal
• Date: 2011

Authors

Tania S C R Rebelo (Author) Other; Sofia A A Almeida (Author) Other; Rafaela R L Guerreiro (Author) Other; Conceicao C B S M Montenegro (Author) FFUP; Goreti G F Sales (Author) Other

Journal

Title: Microchemical Journal

Vol. 98

Pages: 21-28

ISSN: 0026-265X

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 20 Citations

Scopus - 25 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-002-S85

DOI: 10.1016/j.microc.2010.10.006

Abstract (EN): This work proposes a new biomimetic sensor material for trimethoprim. It is prepared by means of radical polymerization, having trimethylolpropane trimethacrylate as cross-linker, benzoyl peroxide as radicalar iniciator, chloroform as porogenic solvent, and methacrylic acid and 2-vinyl pyridine as monomers. Different percentages of sensor in a range between 1 and 6% were studied. Their behavior was compared to that obtained with ion-exchanger quaternary ammonium salt (additive tetrakis(p-chlorophenyl)borate or tetraphenylborate). The effect of an anionic additive in the sensing membrane was also tested. Trimethoprim sensors with 1% of imprinted particles from methacrylic acid monomers showed the best response in terms of slope (59.7 mV/decade) and detection limit (4.01 x 10(-7) mol/L). These electrodes displayed also a good selectivity towards nickel, manganese aluminium. ammonium, lead, potassium, sodium, iron, chromium, sulfadiazine, alanine, cysteine, tryptophan, valine and glycine. The sensors were not affected by pH changes from 2 to 6. They were successfully applied to the analysis of water from aquaculture.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8