Oxidative Stress and Antioxidant Defenses

Code:

B4043

Acronym:

B4043

Keywords
Classification	Keyword
OFICIAL	Biology

Instance: 2013/2014 - 2S

Active?	Yes
Responsible unit:	Department of Biology
Course/CS Responsible:	Master in Cell and Molecular Biology

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
M:BCM	23	Official Study Plan until 2023/2024	1	-	6	42	162

Teaching language

Portuguese

Objectives

To enable students to identify the factors affecting the stress response and the production pathways of the reactive oxygen species. To describe the enzymatic and non-enzymatic antioxidant defense systems and explain their physiological function. To provide students with knowledge of the physiological and biochemical processes underlying the damage caused by abiotic stresses and the mechanisms of adaptation and acclimation of plants and animals to stressful situations. To identify strategies to increase the tolerance of plants and animals to certain types of stress.

Learning outcomes and competences

 

Upon conclusion of the course, the student should be able to:

- Identify the reactive oxygen species, cellular sites of production and the situations that contribute to its increased production and accumulation.

- Know the enzymatic antioxidant defense system and non enzymatic.

-Recognize the main changes that arise in plants and animals when exposed to different abiotic stress situations.

Working method

Presencial

Program

Environmental factors as ontogeny and stress factors. Tolerance and adaptation to stress. Cross tolerance. Production of reactive oxygen species (ROS) and oxidative stress. Types of ROS, cellular places of production and metabolic pathways involved. System of antioxidant defense: enzymatic and non enzymatic. Antioxidant network. Differences and similarities between plants and animals. Stresses and increased production of ROS. Symptoms of oxidative damage. ROS as signal molecules in inducing resistance to stress. Common aspects of the response of animals and plants to specific situations of stress. Plant responses and adaptations to abiotic stress.

Mandatory literature

000077652. ISBN: 0-19-854137-6
000103971. ISBN: 978-0-87893-866-7

Teaching methods and learning activities

Lectures and laboratory classes. Lectures are presented in slideshow using the software "PowerPoint". Laboratory classes enable the acquisition of specific skills, including those arising from the implementation of practical experiments.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	75,00
Participação presencial	25,00
Total:	100,00

Eligibility for exams

Laboratory classes are mandatory.

Calculation formula of final grade

Final grade: final exam covering theory and practical subjects graded to 15 points and oral presentation of a program subject graded to 5 points