Recent advances on computational proteomics

• Tipo: Artigo em Revista Científica Internacional
• Data: 2009

Autores

Sousa, SF (Autor) FCUP; Cerqueira, NMFSA (Autor) FCUP; Perez, MAS (Autor) Outra; Moreira, IS (Autor) Outra; Ribeiro, AJM (Autor) Outra; Neves, ARAP (Autor) Outra; Ramos, MJ (Autor) FCUP; Fernandes, PA (Autor) FCUP

Revista

Título: World Academy of Science, Engineering and Technology

Vol. 56

Páginas: 376-386

ISSN: 2010-376X

Editora: World Academy of Science Engineering and Technology

Indexação

ISI Web of Knowledge

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-007-X1N

Abstract (EN): In this work we report the recent progresses that have been achieved by our group in the last half decade on the field of computational proteomics. Specifically, we discuss the application of Molecular Dynamics Simulations and Electronic Structure Calculations in drug design, in the clarification of the structural and dynamic properties of proteins and enzymes and in the understanding of the catalytic and inhibition mechanism of cancer-related enzymes. A set of examples illustrate the concepts and help to introduce the reader into this important and fast moving field.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11