Molecular Epidemiology of Pseudomonas aeruginosa Clinical Isolates from Portuguese Central Hospital

• Tipo: Artigo em Revista Científica Internacional
• Data: 2008

Autores

Fonseca, AP (Autor) Outra; Correia, P (Autor) Outra; Extremina, CI (Autor) Outra; Sousa, JC (Autor) Outra; Tenreiro, R (Autor) Outra; Barros H (Autor) FMUP

Revista

Título: Folia Microbiologica

Vol. 53 Nº 6

Páginas: 540-546

ISSN: 0015-5632

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 7 Citações

Scopus - 7 Citações

Outras Informações

ID Authenticus: P-004-390

DOI: 10.1007/s12223-008-0086-y

Abstract (EN): The relatedness between clinical isolates of P. aeruginosa obtained from patients during their stay in a Portuguese Central Hospital was evaluated. Genotypic fingerprinting (M13-PCR), phenotypic methods (biotyping and antibiotyping) and epidemiological information (spatial and temporal links) were used to evaluate the relatedness between 88 clinical isolates (68 patients), selected randomly out of 189. Sixty-two M13 types were found, 12 of them containing isolates from more than one patient. Thirty-four antibiotypes were found, as well as a significant association (p < 0.05) between epidemic isolates and multiresistance patterns. The nosocomial transmission of P. aeruginosa strains may be limited since M 13 typing demonstrated a high degree of diversity among all the isolates, suggesting the occurrence of mainly independent infectious episodes. The results show the possible occurrence of cross-acquisition, cross-colonization and cross-infection and suggest an epidemic population structure for P. aeruginosa in this hospital.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7