Molecular Epidemiology of Pseudomonas aeruginosa Clinical Isolates from Portuguese Central Hospital

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Fonseca, AP (Author) Other; Correia, P (Author) Other; Extremina, CI (Author) Other; Sousa, JC (Author) Other; Tenreiro, R (Author) Other; Barros H (Author) FMUP

Journal

Title: Folia Microbiologica

Vol. 53 No. 6

Pages: 540-546

ISSN: 0015-5632

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 7 Citations

Other information

Authenticus ID: P-004-390

DOI: 10.1007/s12223-008-0086-y

Abstract (EN): The relatedness between clinical isolates of P. aeruginosa obtained from patients during their stay in a Portuguese Central Hospital was evaluated. Genotypic fingerprinting (M13-PCR), phenotypic methods (biotyping and antibiotyping) and epidemiological information (spatial and temporal links) were used to evaluate the relatedness between 88 clinical isolates (68 patients), selected randomly out of 189. Sixty-two M13 types were found, 12 of them containing isolates from more than one patient. Thirty-four antibiotypes were found, as well as a significant association (p < 0.05) between epidemic isolates and multiresistance patterns. The nosocomial transmission of P. aeruginosa strains may be limited since M 13 typing demonstrated a high degree of diversity among all the isolates, suggesting the occurrence of mainly independent infectious episodes. The results show the possible occurrence of cross-acquisition, cross-colonization and cross-infection and suggest an epidemic population structure for P. aeruginosa in this hospital.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7