Neuromuscular Blockade Control based on a New Patient Identification Procedure

• Type: Article in International Scientific Journal
• Date: 2025

Authors

Hugo Alonso (Author) Other; Sousa, CNS (Author) Other; Mendonça, F (Author) Other; Rocha, P (Author) FEUP

Journal

Title: WSEAS Transactions on Biology and Biomedicine

Vol. 22

Pages: 343-350

ISSN: 1109-9518

Publisher: World Scientific and Engineering Academy and Society

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-019-W5S

DOI: 10.37394/23208.2025.22.32

Abstract (EN): In this paper, we consider a reduced parameter (RP) model for the effect of the drug atracurium on the level of neuromuscular blockade (NMB) of patients undergoing general anesthesia. We propose a new identification procedure to estimate the patient-dependent parameters of the RP model and present two NMB control laws based on it. The first is a closed-loop law and is referred to as the total-mass control law. The second is an open-loop law based on the inversion of the RP model in steady state. We conduct an experimental study in which we compare the control results obtained from the two approaches. © 2025 Elsevier B.V., All rights reserved.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 0