Insights into the Chemical Composition and In Vitro Bioactive Properties of Mangosteen (Garcinia mangostana L.) Pericarp

• Tipo: Artigo em Revista Científica Internacional
• Data: 2023

Autores

Albuquerque, BR (Autor) Outra; Dias, MI (Autor) Outra; Pinela, J (Autor) Outra; Calhelha, RC (Autor) Outra; Pires, TCSP (Autor) Outra; Alves, MJ (Autor) Outra; Correa, RCG (Autor) Outra; Ferreira, ICFR (Autor) Outra; Beatriz B P P Oliveira (Autor) FFUP; Barros, L (Autor) Outra

Revista

Título: Foods

Vol. 12

Página Final: 994

Editora: MDPI

Indexação

ISI Web of Knowledge - 0 Citações

Scopus

Outras Informações

ID Authenticus: P-00X-ZBQ

DOI: 10.3390/foods12050994

Abstract (EN): The industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 15