Recommendations Favoring Anal Cytology as a Method for Anal Cancer Screening: A Systematic Review

• Tipo: Artigo em Revista Científica Internacional
• Data: 2019

Autores

Albuquerque, A (Autor) Outra; Rios, E (Autor) Outra; Fernando Schmitt (Autor) FMUP

Revista

Título: Cancers

Vol. 11

Página Final: 1942

ISSN: 2072-6694

Editora: MDPI

Indexação

ISI Web of Knowledge - 33 Citações

Scopus - 34 Citações

Outras Informações

ID Authenticus: P-00R-F6A

DOI: 10.3390/cancers11121942

Abstract (EN): Clinicians are increasingly facing the decision of performing anal cancer screening in high-risk groups. Anal cytology is commonly the first approach. We systematically reviewed recommendations favoring anal cytology for anal cancer screening. Three databases were searched: PubMed, Scopus, and Embase, from January 2007 to 12 September 2019. The references cited by the retrieved articles and the websites of relevant organizations were also searched without language restrictions. Studies reporting guidelines from regional or national societies, institutes, or groups were included. Eight papers met the inclusion criteria and were selected, five were from the United States of America (USA) and three from Europe. There were no national recommendations published. There was one guideline specifically for solid-organ transplant recipients. The other seven targeted HIV-positive patients, with HIV-positive men who have sex with men (MSM) included as a screening group in all of these. Two recommendations favored screening in all HIV-positive patients. Five recommendations targeting HIV-positive patients made considerations about the cytology follow-up, recommending at least annual cytology in case of a normal result, and in case of squamous cytological abnormalities, a referral for anoscopy/high-resolution anoscopy. There were no recommendations for upper and lower age limits for screening. In conclusion, several societies recommend anal cancer screening using anal cytology in HIV-positive MSM patients. There is a lack of screening recommendations for other high-risk groups, with only one society recommending screening in transplant recipients.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11