Numerical study of wall shear stress-based descriptors in the human left coronary artery

• Type: Article in International Scientific Journal
• Date: 2016

Authors

S. I. S. Pinto (Author) FEUP; J. B. L. M. Campos (Author) FEUP

Journal

Title: Computer Methods in Biomechanics and Biomedical Engineering

Vol. 19 No. 13

Pages: 1443-1455

ISSN: 1025-5842

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 13 Citations

Scopus - 24 Citations

Scientific classification

FOS: Engineering and technology > Mechanical engineering

Associated Projects

PTDC/EME-MFE/102974/2008 - Estudo numérico e experimental do escoamento de sangue no interior de stents implantados em artérias

Other information

Authenticus ID: P-00K-RDZ

DOI: 10.1080/10255842.2016.1149575

Abstract (EN): The present work is about the application of wall shear stress descriptors – time averaged wall shear stress (TAWSS), oscillating shear index (OSI) and relative residence time (RRT) – to the study of blood flow in the left coronary artery (LCA). These descriptors aid the prediction of disturbed flow conditions in the vessels and play a significant role in the detection of potential zones of atherosclerosis development. Hemodynamic descriptors data were obtained, numerically, through ANSYS® software, for the LCA of a patient-specific geometry and for a 3D idealized model. Comparing both cases, the results are coherent, in terms of location and magnitude. Low TAWSS, high OSI and high RRT values are observed in the bifurcation – potential zone of atherosclerosis appearance. The dissimilarities observed in the TAWSS values, considering blood as a Newtonian or non-Newtonian fluid, releases the importance of the correct blood rheologic caracterization. Moreover, for a higher Reynolds number, the TAWSS values decrease in the bifurcation and along the LAD branch, increasing the probability of plaques deposition. Furthermore, for a stenotic LCA model, very low TAWSS and high RRT values in front and behind the stenosis are observed, indicating the probable extension, in the flow direction, of the lesion.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 13