The effects of surface properties on escherichia coli adhesion are modulated by shear stress

• Type: Article in International Scientific Journal
• Date: 2014

Authors

J. M. R. Moreira (Author) FEUP; J. D. P. Araújo (Author) FEUP; J. M. Miranda (Author) FEUP; M. Simões (Author) FEUP; L. F. Melo (Author) FEUP; F. J. Mergulhão (Author) FEUP

Journal

Title: Colloids and Surfaces B: Biointerfaces

Vol. 123

Pages: 1-7

ISSN: 0927-7765

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 15 Citations

ISI Web of Science

Scopus - 26 Citations

Scientific classification

FOS: Engineering and technology

CORDIS: Technological sciences

Associated Projects

Filmstart - Estudo das condições iniciais que controlam a formação de biofilmes

PTDC/EQU-FTT/105535/2008 - Sujamento e limpeza de micro canais

Other information

Authenticus ID: P-009-XAJ

DOI: 10.1016/j.colsurfb.2014.08.016

Abstract (EN): The adhesion of Escherichia colito glass and polydimethylsiloxane (PDMS) at different flow rates (between 1 and 10 ml s−1) was monitored in a parallel plate flow chamber in order to understand the effect of surface properties and hydrodynamic conditions on adhesion. Computational fluid dynamics was used to assess the applicability of this flow chamber in the simulation of the hydrodynamics of relevant biomedical systems. Wall shear stresses between 0.005 and 0.07 Pa were obtained and these are similar to those found in the circulatory, reproductive and urinary systems. Results demonstrate that E. coli adhesion to hydrophobic PDMS and hydrophilic glass surfaces is modulated by shear stress with surface properties having a stronger effect at the lower and highest flow rates tested and with negligible effects at intermediate flow rates. These findings suggestthat when expensive materials or coatings are selected to produce biomedical devices, this choice should take into account the physiological hydrodynamic conditions that will occur during the utilization of those devices.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7